TAILIEUCHUNG - Characterization and antifungal susceptibility profile of candida species isolated from candiduria cases in a tertiary care hospital, Kolkata

Candida species are unusual cause of urinary tract infections in healthy individuals, but common in hospital setting or among patients with predisposing factors. The isolation of Candida from urine is challenging both for clinician and microbiologist as to whether the candiduria represents colonization or urinary tract infection. Species identification of Candida is also important as non albicans Candida are on rise in recent years which are more resistant to antifungal drugs and as a result morbidity and mortality is also increasing. The objective of this study was to determine the prevalence of Candida species causing UTI, analyze various risk factors associated with candiduria and their antifungal susceptibility pattern. A total of 1860 urine samples from clinically suspected cases of urinary tract infection were analysed in a tertiary care Hospital during a period of one year. 105 Candida isolates were obtained from these urine samples and species identification was done following standard laboratory protocol. Antifungal susceptibility testing was performed by disc diffusion method following CLSI guideline M-44A. Among all suspected cases of urinary tract infection, candiduria was diagnosed in cases. Candida tropicalis 44(42%) was the predominant isolate followed by Candida albicans38(36%), Candida glabrata-14(13%), Candida parapsilosis-07(07%) and Candida krusei02(02%). The antifungal susceptibility pattern showed that Candida isolates were more resistant to Fluconazole-39(37%), followed by Itraconazole-30 (). Fluconazole resistance was more common among non albicans Candida (41%) than Candida albicans (29%). Our study reflects a change in trend with shift towards non-albicans candida replacing Candida albicans as the predominant cause of candiduria. Non albicans Candida species are more resistant to antifungal drugs compared to C. albicans. | Characterization and antifungal susceptibility profile of candida species isolated from candiduria cases in a tertiary care hospital, Kolkata

• Y khoa - Dược
• Antifungal susceptibility profile
• Candida species
• Candida species isolated
• Candiduria cases
• Tertiary care hospital
• Antifungal susceptibility
• Dermatophytic infection
• Clinico mycologic profile
• Antifungal susceptibility pattern
• North western zone of Rajasthan
• Antifungal resistance
• Candida albicans
• Oral candidiasis
• Candida isolates obtained
• Patients attending outpatient department
• Various Candida species
• Candida and its comparison
• Steroids or other immunosuppressive agents
• Non albicans Candida
• Hospitalised patients
• Candida non albicans
• MSMALDI TOF
• Patients in ICUs
• Anti fungal resistance profile
• Co prevalence of dengue
• Salmonella infections
• Tertiary care hospital in south India
• Febrile patients
• HIV infection
• Prevalence of HIV infection
• Pregnant women
• Tertiary care hospital Akola
• Tertiary care hospital at Akola
• Surveillance of hospital acquired infection
• Hospital acquired infection
• Frequently handled surfaces
• Tertiary care teaching hospital
• Multidrug resistant organisms
• MDR pseudomonas aeruginosa
• Nosocomial infection
• Burden in ICU
• Burn units of a Tertiary Care Hospital
• Aedes mosquito
• Capture ELISA
• Seroprevalence of dengue
• Dengue in a tertiary care hospital
• Biomedical waste
• Hospital staff
• Biomedical waste management practices
• Tertiary health care institute
• Dermatophytes in teaching hospital
• Profile of dermatophytes
• Clinical profile
• Prevalent in this region
• Health careassociated infections
• Antimicrobial susceptibility testing
• Health care worker
• Health care workers
• Water quality
• Faecal coliforms
• Most Probable no
• Tertiary care hospital of northern India
• Water quality in hospital
• Biomedical waste management
• Knowledge attitude
• Housekeeping individuals are working
• Needle stick injuries
• NSI prevention program
• Prophylaxis and treatment
• Hand hygiene
• Hospital acquired infections
• Practices among postgraduates
• Crris in a Tertiary Care Hospital
• Microsoft excel 2010 software
• Urinary tract infection
• Incidence of urinary tract infection
• Antenatal patients attending
• Patients attending our hospital viz
• Cell phones
• Health care associated infections
• Bacterial load on cellphones
• Patient attendants
• Resident flora
• Steps of hygienic handwash
• Tertiary care medical college hospital
• Hand hygiene to reduce transient flora
• Synergistic activity
• Nanoparticles with antibiotics
• Multi drug resistant organisms
• Silver nanoparticles
• Gram positive bacteria
• Antibiotic susceptibility pattern
• Methicillin resistant staphylococcus aureus
• Bio medical waste
• Practises on biomedical
• Fungal sepsis
• Fungal blood stream infection
• Fungal septicaemia
• New born at tertiary
• Klebsiella pneumoniae
• Plasmid mediated AmpC β lactamases
• Multidrug resistance
• Teaching hospital
• Burn wound infection
• Pseudomonas aeruginosa
• Burn care unit
• Klebsiella spp dual isolate
• Bacteriological profile
• Antibiogram of gram positive cocci isolated
• Gram positive cocci isolated
• Catheter associated urinary tract infection
• Tissue culture plate method
• Congo red agar
• Staphylococcus aureus
• Biofilm formation in staphylococcus aureus
• Clinico mycological study
• Humid climates
• Nail scrapings and hair follicles
• Patients presenting
• Diabetes mellitus
• Parasitic infestation
• Diabetic patients
• Parasitic infestation in diabetic patients
• Prevalence of parasitic infestation