TAILIEUCHUNG - Detection of extended spectrum β Lactamase and Amp C β Lactamase resistance in the gram negative bacterial isolates of ventilator associated pneumonia

Ventilator-associated pneumonia (VAP) is an important nosocomial infection in mechanically ventilated patients at intensive care unit (ICU). The administration of accurate and timely initial empirical antibiotic therapy is essential to reduce the morbidity and mortality from Ventilator-associated pneumonia. Initial empiric antimicrobial therapy for VAP greatly depends on the type of causative pathogen and its resistance pattern. During the six months study period, 196 patients received mechanical ventilation. Endo tracheal aspirates were collected from 22 mechanically ventilated patients with suspected ventilator associated pneumonia. 19 organisms were isolated. All Cefoxitin resistant isolates were studied for the presence of plasmid mediated AmpC beta-lactamase enzyme by Inhibitor disk based method and inducible AmpC beta-lactamase production by Ceftazidime-imipenem antagonism test (CIAT).ESBL production in the gram negative isolates was detected by Phenotypic Confirmatory Test. Incidence rate of VAP was . Klebsiella pneumoniae (26%) was the most common organism followed by Pseudomonas aeruginosa (21%) and Acinetobacter spp (16%). (53%) of Gram negative isolates were positive for ESBL production. (6%) was positive for plasmid mediated Amp C beta lactamase production and (6%) was positive for inducible Amp C beta lactamase production. Due to the increasing incidence of drug-resistant organisms, VAP requires an early diagnosis and appropriate antibiotic treatment, to prevent mortality and morbidity. Hence, knowing the bacterial isolates and their antibiotic resistance pattern is essential to improve the clinical outcome of VAP. | Detection of extended spectrum β Lactamase and Amp C β Lactamase resistance in the gram negative bacterial isolates of ventilator associated pneumonia

• Y khoa - Dược
• β Lactamase
• Gram negative bacteria
• Extended spectrum β Lactamase
• Amp C β Lactamase resistance
• Gram negative bacterial isolates
• Ventilator associated pneumonia
• Better β Lactam/β lactamase inhibitor combination
• Spare carbapenem drugs
• In vitro susceptibility pattern
• β lactamases triggered extensive
• Life threatening diseases
• Salmonella miami
• Antimicrobial drug resistance
• β lactamase resistant genes isolated
• Diarrhoeic piglets
• Salmonella enterica serovar miami possessing
• Antibiotic abuse
• Producing bacteria
• Clinical samples
• Tần suất gen độc lực đường ruột
• Gen độc lực đường ruột
• Tính kháng colistin
• Chủng Escherichia Coli
• β lactamase phổ rộng
• β lactamase phân lập từ thực phẩm
• Bệnh nhân tiêu chảy
• Khảo sát trực khuẩn gram âm
• Enterobacteriaceae sinh men β lactamase
• Esbl Extended Spectrum Βlactamase
• Kháng sinh đồ
• Xác định kiểu gen β lactamase
• Kiểu gen β lactamase phổ mở rộng
• Các chủng Escherichia coli
• Escherichia coli phân lập từ người
• Escherichia coli phân lập từ bệnh phẩm
• Multi drug resistance
• Hospitalized patients in Gurugram
• Extended spectrum β lactamase production in uropathogens
• Urinary tract infection
• Multidrug resistant uropathogenic E coli
• Role of β lactamase
• Classes of antibiotics
• Metalo beta lactamase
• Acinetobacter species
• Metallo β lactamase producing
• Acinetobacter in clinical specimens
• Produce extended spectrum beta lactamase
• Aeromonas spp
• MAR index
• Extended spectrum β lactamases
• ESBL producer
• Extended spectrum β lactamase Aeromonas spp
• Antimicrobial susceptibility pattern
• AmpC β lactamase
• Inhibitor based test
• AmpC disc test
• Comparison of two phenotypic methods
• Escherichia coli
• AmpC beta lactamase detection
• Hội nghị Khoa học Bệnh viện An Giang
• Bài viết về y học
• Trực khuẩn Gram âm sinh men β lactamase
• Men beta lactamase phổ rộng
• Nhiễm khuẩn hô hấp
• Đề kháng kháng sinh
• Gen mã hóa ESBL
• Gen bla CTX M
• Antibiotic resistance
• Inhibitor protein
• Mediated antibiotic
• Tạp chí Y học
• Trực khuẩn đường ruột sinh β lactamase
• Đường tiêu hóa người lành mạnh
• Klebsiella spp
• Gen kháng thuốc mã hóa enzym ESBL
• Salmonella spp
• Raw milk
• InvA blaTEM
• Extended spectrum β lactamase producing
• Occurrence and characterization
• Imipenem resistant E coli
• PCR detection
• BlaIMP Gene
• Metallo β Lactamase
• Tần suất một số gen mã hóa
• Gen mã hóa yếu tố độc
• Yếu tố độc của Escherichia coli
• Sinh β lactamase phổ mở rộng
• Gen mã hóa
• Pseudomonas aeruginosa
• Extended spectrum of β lactamase (ESBL)
• Metallo β lactamase (MBL)
• Tertiary care centre
• Phenotypic detection
• Double disc diffusion test
• Klebsiella pneumoniaee in urinary isolates
• Clavulanic acid and cefotaxime
• Staphylococcus sciuri
• Klebsiella pneumoniae
• Kinetic parameters
• Two pathogenic ba
• Tỷ lệ mang gen mã hóa enzym ESBL
• Tỷ lệ mang gen mã hóa Amp C β lactamase
• Vi khuẩn Escherichia coli
• Phân lập vi khuẩn Escherichia coli
• Vi khuẩn Escherichia coli phân lập từ chó
• E coli sinh enzyme β lactamase phổ rộng
• Vi khuẩn gây bệnh nguy hiểm
• Công tác sản xuất thuốc kháng sinh
• Chủng vi khuẩn đề kháng kháng sinh
• Chủng xạ khuẩn SS47
• Vi khuẩn Gram âm đa kháng thuốc
• Chủng vi khuẩn E coli
• New Delhi metallo β lactamase
• Carbapenem cải tiến EDTA CIM
• Phương pháp định tính Kirby Bauer