TAILIEUCHUNG - Alteration of blood adrenocorticotropic hormone and cortisol level in rheumatoid arthritis patients

Objectives: To investigate whether the pituitary-adrenal axis may be altered under long-term inflammation of rheumatoid arthritis as well as the effect of steroid administration. Subjects and methods: Concentration of blood adrenocorticotropic hormone and cortisol were measured in 140 rheumatoid arthritis patients and 60 people used as control group. | Journal of military pharmaco-medicine n08-2018 ALTERATION OF BLOOD ADRENOCORTICOTROPIC HORMONE AND CORTISOL LEVEL IN RHEUMATOID ARTHRITIS PATIENTS Truong Quang Pho1; Le Anh Thu2 SUMMARY Objectives: To investigate whether the pituitary-adrenal axis may be altered under long-term inflammation of rheumatoid arthritis as well as the effect of steroid administration. Subjects and methods: Concentration of blood adrenocorticotropic hormone and cortisol were measured in 140 rheumatoid arthritis patients and 60 people used as control group. Results: Concentration of blood adrenocorticotropic hormone and cortisol in rheumatoid arthritis patients at 8 am and 11 pm were significantly lower than those in control group. Among rheumatoid arthritis patients, concentration of blood adrenocorticotropic hormone and cortisol in steroid users were significantly lower than those in non-steroid users. Conclusion: These results have provided evidence that the impairment of the pituitary-adrenal axis in rheumatoid arthritis patients was due to not only chronic inflammation but also steroid using. * Keywords: Rheumatoid arthritis; Adrenocorticotropic hormone; Cortisol. INTRODUCTION Rheumatoid arthritis (RA) is one of the most common arthritis that affects 1% population [1]. RA is a long-term autoimmune disorder that primarily affects joints by chronic inflammation. It typically results in warm, swollen, and painful joints. Pain and stiffness often worsen following rest, especially in the early morning. Most commonly, the wrist and hands are involved, with the same joints typically involved on both sides of the body [2]. The disease may result in a low red blood cell count, inflammation around the lungs, and inflammation around the heart. Fever and low energy may also be present often, symptoms come on gradually over weeks to months [2]. While the cause of rheumatoid arthritis is not clear, it is believed to involve a combination of genetic and environmental factors [1]. The underlying .

• Y khoa - Dược
• Rheumatoid arthritis patients
• Blood adrenocorticotropic
• Adrenocorticotropic hormone
• Pituitary adrenal axis
• Hypothalamo pituitary adrenal
• Serum levels of TNF α cytokines
• Serum level TNF alpha in patients
• Tumor necrosis factor alpha in rheumatoid arthritis patients
• Laboratory variables in rheumatoid arthritis patients group
• Rheumatoid arthritis
• DAS 28 score
• Patients with rheumatoid arthritis
• Serum midkine level
• Comparative risk of diabetes mellitus
• Diabetes mellitus in patients
• Rheumatoid arthritis treated
• Targeted synthetic disease modifying drugs
• Rheumatoid arthritis treated with biologic
• BMC Pulmonary Medicine
• Interstitial lung disease
• Velcro sound
• Diagnostic accuracy
• BMC Musculoskeletal Disorders
• Psoriatic arthritis
• Magnetic resonance imaging
• Random forest based segmentation
• Hand muscle
• Barriers and facilitators
• Physical activity
• Axial Spondyloarthritis
• Patient reported outcome measures
• Disease activity index
• Biologics therapy
• Metatarsophalangeal joints
• Fibromyalgic rheumatoid
• Reliably discriminate
• Inflammatory disease
• trình bày báo cáo
• tài liệu báo cáo khoa học
• báo cáo y học
• nghiên cứu y học
• kiến thức y học
• Tạp chí khoa học
• Tạp chí y dược
• Y dược quân sự
• Disease activity
• Bone mineral density
• Serum tumor necrosis
• Tumor necrosis factor α
• Interleukin 17
• Interleukin 6
• Synovial fibroblasts
• Early Rheumatoid Arthritis
• Dysfunctional clinical features
• Temporomandibular disorders
• Oral implications
• Myofacial pain
• Autoimmune diseases
• MicroRNA expression analysis
• Inhibits post transcriptionally
• Human plasma healthy controls
• Tranexamic acid
• Total knee arthroplasty
• Preemptive antifibrinolysis
• Orthotic device
• Outcome assessment
• In shoe plantar pressure measurements
• Fibroblast like synoviocytes
• Inflammatory joint diseases
• Detailed functional
• Morning stiffness
• Systematic review
• Beliefs about medicines
• Illness representation
• Satisfaction with information
• Disease modifying anti rheumatic drug
• Treat to target
• MRI synovitis score
• Molecular predictors of response
• Risk factors
• Active systemic inflammation
• Vertebral fracture
• Biologic therapy
• Drug survival
• Biologics courses
• Interleukin 17 plays
• Inflammatory response
• IL17F genotypes