TAILIEUCHUNG - Lecture Basics of Meta-analysis

This lecture includes these contents: Basics of meta analysis, the effect measures, the meta analysis, absolute risk reduction, risk on treatment,. Invite you to consult this lecture. | Basics of Meta-analysis Steff Lewis, Rob Scholten Cochrane Statistical Methods Group (Thanks to the many people who have worked on earlier versions of this presentation) Introduction Session plan Introduction Effect measures – what they mean Exercise 1 Meta-analysis Exercise 2 Heterogeneity Exercise 3 Summary Before we start this workshop will be discuss binary outcomes only . dead or alive, pain free or in pain, smoking or not smoking each participant is in one of two possible, mutually exclusive, states There are other workshops for continuous data, etc Where to start You need a pre-defined question “Does aspirin increase the chance of survival to 6 months after an acute stroke?” “Does inhaling steam decrease the chance of a sinus infection in people who have a cold?” Where to start Collect data from all the trials and enter into Revman For each trial you need: The total number of patients in each treatment group. The number of patients who had the relevant outcome in each treatment group Effect measures – what they mean Which effect measure? In Revman you can choose: Relative Risk (RR) = Risk Ratio, Odds Ratio (OR) Risk Difference (RD) = Absolute Risk Reduction (ARR), Risk 24 people skiing down a slope, and 6 fall risk of a fall = 6 falls/24 who could have fallen = 6/24 = ¼ = = 25% risk = number of events of interest total number of observations Odds 24 people skiing down a slope, and 6 fall odds of a fall = 6 falls/18 did not fall = 6/18 = 1/3 = (not usually as %) odds = number of events of interest number without the event Expressing it in words Risk the chances of falling were one in four, or 25% Odds the chances of falling were one third of the chances of not falling one person fell for every three that didn’t fall the chances of falling were 3 to 1 against Do risks and odds differ much? Control arm of trial by Blum 130 people still dyspeptic out of 164 chance of still being dyspeptic risk = 130/164 = ;

• Y khoa - Dược
• Lecture Basics of Meta analysis
• The effect measures
• The Meta analysis
• Absolute Risk Reduction
• Risk on treatment
• Risk assessment
• Hazard identification and risk assessment
• Wastewater treatment
• Hazard identification
• Wastewater treatment plant
• BMC Pediatrics
• Intermediate risk
• Intermediate risk neuroblastoma
• Multidisciplinary treatment
• Prospective phase 2
• Supervision of Treatment
• Tuberculosis
• Methods employed
• Diagnosis of pulmonary
• Clinical diagnosis
• Summary of doctoral thesis
• Risk factors of respiratory distress newborns
• Treatment outcome of respiratory distress newborns
• Pediatrics depatment Bach Mai hospital
• Respiratory distress newborns
• Epidemiology
• Risk Factors
• Hepatocellular Carcinoma
• Surgical Treatment
• Liver Metastases
• BMC Cancer
• High risked neuroblastoma
• Induction therapy
• Treatment response
• Prognostic factor
• Treatment related toxicity
• Model uncertainty
• Parameter uncertainty
• Estimation errors
• Model risk
• Internal governance
• Internal capital adequacy
• Risk capital
• BMC Musculoskeletal Disorders
• Implant associated infections
• Antibiotic treatment
• Orthopaedic devices
• Systemic suppressive antibiotic treatment
• medical research
• Inflammatory Markers
• the Risk
• Coronary Heart Disease
• scientific reports
• treatment
• symptoms
• biochemical
• Severe obesity
• Gender differences
• Lifestyle behavior
• Metabolic syndrome
• Cardiovascular risk factor
• Cardiovascular disease
• Pituitary adenoma
• Treatment planning
• Secondary malignoma risk
• Flattening filter free
• Oropharyngeal squamous cell carcinoma
• Human papillomavirus positive
• Incidence worldwide
• Pathological risk factors
• BMC Pulmonary Medicine
• Tuberculosis outcome
• Lung function
• Lung impairment
• Patient costs
• Treatment outcome
• Inhaled corticosteroids
• Risk of pneumonia
• Incidence risk ratio
• Gastroesophageal reflux
• Risk management
• Tax administration
• Tax compliance
• Risk classification criteria
• Modernizing tax administration
• Non reporting tax obligations
• Adherence
• antiretroviral treatment
• Tuberculosis Control
• jointly reviewed
• managerial weakness
• Parking Arrangements
• Disregarded Entities
• Treatment Responses
• Antiviral Treatment
• Immunological Pathogenesis
• Septic Reactions
• Economic Dispatch Applications
• Decomposition Approach
• facilities studied
• treatment outcomes
• reported complete
• Drug treatment
• short course
• treatment failure
• health and nutrition
• education
• gen
• HIV associated
• attending Medical
• survival among
• Emerging Infectious