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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Genome comparison of two Coccolithoviruses | Virology Journal BioMed Central Research Genome comparison of two Coccolithoviruses Michael J Allen1 Declan C Schroeder2 Andrew Donkin1 Katharine J Crawfurd1 and William H Wilson 1 Open Access Address Plymouth Marine Laboratory Prospect Place The Hoe Plymouth PL1 3DH UK and 2Marine Biological Association Citadel Hill Plymouth PL1 2PB UK Email Michael J Allen - mija@pml.ac.uk Declan C Schroeder - dsch@mba.ac.uk Andrew Donkin - m.donkin@plymouth.ac.uk Katharine J Crawfurd - kacra@pml.ac.uk William H Wilson - whw@pml.ac.uk Corresponding author Published 22 March 2006 Received 25 October 2005 Accepted 22 March 2006 Virology Journal2006 3 15 doi 10.1186 1743-422X-3-15 This article is available from http www.virologyj.com content 3 1 15 2006Allen et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The Coccolithoviridae is a recently discovered family of viruses that infect the marine coccolithophorid Emiliania huxleyi. Following on from the sequencing of the type strain EhV-86 we have sequenced a second strain EhV-163. Results We have sequenced approximately 80 of the EhV-163 genome equating to more than 200 full length CDSs. Conserved and variable CDSs and a gene replacement have been identified in the EhV-86 and EhV-163 genomes. Conclusion The sequencing of EhV-163 has provided a wealth of information which will aid the re-annotating of the EhV-86 genome and identified a gene insertion in EhV-163. Background We recently determined the whole genome sequence of the Coccolithoviridae strain EhV-86 a giant dsDNA algal virus from the family Phycodnaviridae that infects the marine coccolithophorid Emiliania huxleyi 1 . Core genes common to nuclear-cytoplasmic large DNA virus NCLDV genomes were identified and .