TAILIEUCHUNG - Báo cáo sinh học: "Results of a whole genome scan targeting QTL for growth and carcass traits in a Piétrain × Large White intercross"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học thế giới đề tài: Results of a whole genome scan targeting QTL for growth and carcass traits in a Piétrain × Large White intercross | 371 Genet Sei. Evol. 34 2002 371-387 INRA EDP Sciences 2002 DOI gse 2002013 Original article Results of a whole genome scan targeting QTL for growth and carcass traits in a Piétrain X Large White intercross Carine Nezer Laurence Moreau DannY Wagenaar Michel Georges Department of Genetics FacultY of VeterinarY Medicine UniversitY of Liège B43 20 Bd de Colonster 4000 Liège Belgium Received 13 November 2001 accepted 29 JanuarY 2002 Abstract - We herein report the results of a whole genome scan performed in a Piétrain X Large White intercross counting 525 offspring to map QTL influencing economically important growth and carcass traits. We report experiment-wide significant lod scores for meatiness and fat deposition on chromosome SSC2 and for average daily gain and carcass length on chromosome SSC7. Additional suggestive lod scores for fat deposition are reported on chromosomes SSC1 SSC7 and SSC13. A significant dominance deviation was found for the QTL on SSC1 while the hypothesis of an additive QTL could not be rejected for the QTL on SSC7 and SSC13. No evidence for imprinted QTL could be found for QTL other than the one previously reported on SSC2. QTL mapping pig growth traits carcass traits 1. introduction The availability of genome-wide microsatellite maps for an increasing number of species has spurred efforts to dissect the molecular basis of the genetic variation for a broad range of medically agriculturally or fundamentally important heritable quantitative traits . 1 6 . Interest in QTL mapping experiments has been considerable in livestock production science because of the opportunities to exploit mapping data in more effective marker assisted selection MAS schemes. Implementation of QTL mapping experiments in livestock species has been facilitated by i the availability of large data sets of phenotypic records collected as part of most breeding programs ii the extensive groundwork invested in the estimation of variance components .

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