TAILIEUCHUNG - Báo cáo sinh học: " Genome-wide identification of QTL for age at puberty in gilts using a large intercross F2 population between White Duroc · Erhualian"

Tuyển tập các báo cáo nghiên cứu về sinh học được đăng trên tạp chí sinh học quốc tế đề tài: Genome-wide identification of QTL for age at puberty in gilts using a large intercross F2 population between White Duroc · Erhualian | Genet. Sel. Evol. 40 2008 529-539 INRA EDP Sciences 2008 DOI gse 2008019 Available online at Original article Genome-wide identification of QTL for age at puberty in gilts using a large intercross F2 population between White Duroc X Erhualian Guangcheng Yang Jun Ren Shijun Li Huirong Mao Yuanmei Guo Zhengzhi Zou Dongren Ren Junwu Ma Lusheng Huang Key Laboratory for Animal Biotechnology of Jiangxi Province and the Ministry of Agriculture of China Jiangxi Agricultural University Nanchang 330045 P. R. China Received 1st February 2008 accepted 18 April 2008 Abstract - Puberty is a fundamental development process experienced by all reproduc-tively competent adults yet the specific factors regulating age at puberty remain elusive in pigs. In this study we performed a genome scan to identify quantitative trait loci QTL affecting age at puberty in gilts using a White Duroc X Erhualian intercross. A total of 183 microsatellites covering 19 porcine chromosomes were genotyped in 454 F2 gilts and their parents and grandparents in the White Duroc X Erhualian intercross. A linear regression method was used to map QTL for age at puberty via QTLexpress. One 1 genome-wise significant QTL and one genome-wise significant QTL were detected at 114 cM centimorgan on SSC1 and at 54 cM on SSC7 respectively. Moreover two suggestive QTL were found on SSC8 and SSC17 respectively. This study confirmed the QTL for age at puberty previously identified on SSC1 7 and 8 and reports for the first time a QTL for age at puberty in gilts on SSC17. Interestingly the Chinese Erhualian alleles were not systematically favourable for younger age at puberty. age at puberty quantitative trait loci White Duroc Erhualian 1. INTRODUCTION Puberty in females is defined as the time of the first expressed oestrus with ovulation which is a critical development process marking the transition into adulthood. Although the timing of the onset of puberty is influenced by environmental .

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