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Looking at the extensive biological potential of thiazolidine-2,4-dione (TZD) moiety, a new series of thiazolidine-2,4-dione analogues was synthesized. Different spectral techniques (1 H-NMR, IR, MS etc.) were used to confirm the chemical structures of the synthesized analogues. | Design synthesis in silico studies and biological evaluation of 5- E -4- E - substituted aryl alkyl methyl benzylidene thiazolidine-2 4-dione derivatives