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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Sexually transmitted Human Papillomavirus type variations resulting in high grade cervical dysplasia in North-East North Dakota and North-West Minnesota | Virology Journal BioMed Central Open Access Short report Sexually transmitted Human Papillomavirus type variations resulting in high grade cervical dysplasia in North-East North Dakota and North-West Minnesota Lata Balakrishnan1 Ryan Clauson2 Timothy Weiland3 Michelle Bianco4 and Barry Milavetz 1 Address Department of Biochemistry and Molecular Biology University of North Dakota Grand Forks ND USA 2School of Medicine University of North Dakota Grand Forks ND USA 3Department of Pathology University of North Dakota Grand Forks ND USA and 4School of Medicine University of Iowa IA USA Email Lata Balakrishnan - lbalakrishnan@medicine.nodak.edu Ryan Clauson - rclauson@medicine.nodak.edu Timothy Weiland - tweiland@medicine.nodak.edu Michelle Bianco - biancom@uihc.uiowa.edu Barry Milavetz - bmilavetz@medicine.nodak.edu Corresponding author Published 15 June 2006 Received 18 April 2006 Accepted 15 June 2006 Virology Journal 2006 3 46 doi 10.1186 1743-422X-3-46 This article is available from http www.virologyj.cOm content 3 1 46 2006 Balakrishnan et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background A review of Pap smear diagnoses from a reference laboratory in Grand Forks North Dakota over a 3-year period 07 00 to 10 03 revealed a two-fold higher rate of high grade squamous intraepithelial lesion in a community in northwest Minnesota Roseau 0.486 than in northeast North Dakota Grand Forks 0.249 in spite of both having similar rates of low-grade squamous intraepithelial lesion 1.33 vs.1.30 respectively Objectives To identify the different types of HPV present in patient populations showing highgrade dysplasia in Grand Forks ND and