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Tuyển tập các báo cáo nghiên cứu về hóa học được đăng trên tạp chí sinh học quốc tế đề tài : The paradoxical patterns of expression of indoleamine 2,3-dioxygenase in colon cancer | Journal of Translational Medicine BioMed Central Open Access The paradoxical patterns of expression of indoleamine 2 3-dioxygenase in colon cancer Yan-Fang Gao11 2 3 Rui-Qing Peng11 2 Jiang Li1 2 Ya Ding1 2 Xing Zhang1 2 Xiao-Jun Wu1 4 Zhi-Zhong Pan1 4 De-Sen Wan1 4 Yi-Xin Zeng1 2 and Xiao-Shi Zhang 1 2 Address 1State Key Laboratory of Oncology in South China 651 Dongfeng R E 510060 Guangzhou PR China 2Biotherapy Center Cancer Center Sun Yat-sen University 651 Dongfeng R E 510060 Guangzhou PR China 3Department of Medical Oncology Weifang People s Hospital 151 Guangwen Street Kuiwen District 261040 Weifang PR China and 4Department of Abdominal Oncology Cancer Center Sun Yat-sen University 651 Dongfeng R E 510060 Guangzhou PR China Email Yan-Fang Gao - gyf814@tom.com Rui-Qing Peng - gz13724083175@126.com Jiang Li - leejiang@tom.com Ya Ding - dingya@mail.sysu.edu.cn Xing Zhang - xingzhang@hotmail.com Xiao-Jun Wu - wuxiun@mail.sysu.edu.cn Zhi- Zhong Pan - panzhzh@mail.sysu.edu.cn De-Sen Wan - wds-fk@yahoo.com.cn Yi-Xin Zeng - zengyix@mail.sysu.edu.cn Xiao- Shi Zhang - zxs617@hotmail.com Corresponding author fEqual contributors Published 20 August 2009 Received 30 March 2009 Journal of Translational Medicine 2009 7 71 doi 10.1186 1479-5876-7-71 Accepted 20 August 2009 This article is available from http www.translational-medicine.cOm content 7 1 71 2009 Gao et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background One of the putative mechanisms of tumor immune escape is based on the hypothesis that carcinomas actively create an immunosuppressed state via the expression of indoleamine 2 3-dioxygenase IDO both in the cancer cells and in the immune cells among the tumor-draining lymph nodes TDLN . In an attempt to .
