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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: How to compare adequacy of algorithms to control blood glucose in the intensive care unit? | Available online http ccforum.eom content 8 3 151 Commentary How to compare adequacy of algorithms to control blood glucose in the intensive care unit Greet Van den Berghe Professor of Medicine and Chair Department of Intensive Care Medicine Catholic University of Leuven Leuven Belgium Corresponding author Greet Van den Berghe greta.vandenberghe@med.kuleuven.ac.be Published online 15 April 2004 Critical Care 2004 8 151-152 DOI 10.1186 cc2856 This article is online at http ccforum.com content 8 3 151 2004 BioMed Central Ltd Related to Research by Vogelzang et al. see page 201 Abstract Vogelzang et al. retrospectively assessed a derivative marker of blood glucose control over time in the intensive care unit ICU the hyperglycemic index HGI in relation to outcome. The HGI predicted mortality better than other indices of blood glucose control that do not take the duration of hyperglycemia into account. This provided further support to the concept of maintaining normoglycemia with insulin throughout intensive care in order to improve outcome. The HGI was also proposed as a tool to assess performance of glucose control algorithms. This however implies similar sampling frequency for the compared algorithms. Just as we prefer continuous online display of blood pressure and or cardiac output for optimal titration of inotropes and vasopressors a continuous display of blood glucose levels is mandatory for optimal titration of insulin therapy in ICU. We anxiously await the development and validation of such devices. Keywords algorithm glucose insulin intensive care mortality In this issue of Critical Care Vogelzang and coworkers 1 present the results of a retrospective study in which they assessed the relationship between a derivative marker of blood glucose control which they label the hyperglycaemic index HGI and patient outcome in a 12-bed surgical intensive care unit ICU . They define the HGI as the area under the curve AUC of blood glucose above the cutoff of 6.0 mmol l .
