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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Characterization of neutralizing epitopes within the major capsid protein of human papillomavirus type 33 | BioMed Central Virology Journal Research Characterization of neutralizing epitopes within the major capsid protein of human papillomavirus type 33 Stefanie D Roth1 Martin Sapp1 2 3 4 Rolf E Streeck1 and Hans-Christoph Selinka 1 Open Access Address institute for Medical Microbiology Johannes Gutenberg-University 55101 Mainz Germany 2Center for Molecular and Tumor Virology Louisiana State University Health Sciences Center 1501 Kings Highway Shreveport LA 71130 USA 3Feist Weiller Cancer Center Louisiana State University Health Sciences Center 1501 Kings Highway Shreveport LA 71130 USA and 4Department of Microbiology and Immunology Louisiana State University Health Sciences Center 1501 Kings Highway Shreveport LA 71130 USA Email Stefanie D Roth - st_roth@gmx.de Martin Sapp - msapp@lsuhsc.edu Rolf E Streeck - streeck@uni-mainz.de Hans- Christoph Selinka - selinka@uni-mainz.de Corresponding author Published 02 October 2006 Virology Journal 2006 3 83 doi 10.1 I86 I743-422X-3-83 Received 10 August 2006 Accepted 02 October 2006 This article is available from http www.virologyj.Com content 3 1 83 2006 Roth et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Infections with papillomaviruses induce type-specific immune responses mainly directed against the major capsid protein L1. Based on the propensity of the L1 protein to selfassemble into virus-like particles VLPs type-specific vaccines have already been developed. In order to generate vaccines that target a broader spectrum of HPV types extended knowledge of neutralizing epitopes is required. Despite the association of human papillomavirus type 33 HPV33 with cervical carcinomas fine
