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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài:Improving hypertension management through pharmacist prescribing; the rural alberta clinical trial in optimizing hypertension (Rural RxACTION): trial design and methods | Charrois et al. Implementation Science 2011 6 94 http www.implementationscience.eom content 6 1 94 Implementation Science IMPLEMENTATION SCIENCE STUDY PROTOCOL Open Access Improving hypertension management through pharmacist prescribing the rural alberta clinical trial in optimizing hypertension Rural RxACTION trial design and methods 1 2.3 4 2 2 Theresa L Charrois Finlay A McAlister Dale Cooney Richard Lewanczuk Michael R Kolber Norman RC Campbell5 Meagen Rosenthal3 Sherilyn KD Houle3 and Ross TTsuyuki2 3 Abstract Background Patients with hypertension continue to have less than optimal blood pressure control with nearly one in five Canadian adults having hypertension. Pharmacist prescribing is gaining favor as a potential clinically efficacious and cost-effective means to improve both access and quality of care. With Alberta being the first province in Canada to have independent prescribing by pharmacists it offers a unique opportunity to evaluate outcomes in patients who are prescribed antihypertensive therapy by pharmacists. Methods The study is a randomized controlled trial of enhanced pharmacist care with the unit of randomization being the patient. Participants will be randomized to enhanced pharmacist care patient identification assessment education close follow-up and prescribing titration of antihypertensive medications or usual care. Participants are patients in rural Alberta with undiagnosed uncontrolled blood pressure as defined by the Canadian Hypertension Education Program. The primary outcome is the change in systolic blood pressure between baseline and 24 weeks in the enhanced-care versus usual-care arms. There are also three substudies running in conjunction with the project examining different remuneration models investigating patient knowledge and assessing health-resource utilization amongst patients in each group. Discussion To date one-third of the required sample size has been recruited. There are 15 communities and 17 pharmacists actively .
