Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Wertheim cung cấp cho các bạn kiến thức về ngành y đề tài: Significant improvements in self-reported gastrointestinal tolerability, quality of life, patient satisfaction, and adherence with lopinavir/ritonavir tablet formulation compared with soft gel capsules. | AIDS Research and Therapy BioMed Central Short report Open Access Significant improvements in self-reported gastrointestinal tolerability quality of life patient satisfaction and adherence with lopinavir ritonavir tablet formulation compared with soft gel capsules Shannon Schrader1 Susan K Chuck 2 Laurie W Rahn2 Paras Parekh2 and Katherine G Emrich2 Address rrhe Schrader Clinic Houston USA and 2Abbott Virology Abbott Laboratories Abbott Park USA Email Shannon Schrader - doc4jazz@aol.com Susan K Chuck - susan.chuck@abbott.com Laurie W Rahn - laurie.rahn@abbott.com Paras Parekh - paras.parekh@abbott.com Katherine G Emrich - katherine.emrich@abbott.com Corresponding author Published 17 September 2008 Received 17 January 2008 r.11 I IO II-TA-. IAK r 11 Accepted 17 September 2008 AIDS Research and Therapy 2008 5 21 doi l0.ll86 l742-6405-5-2l This article is available from http www.aidsrestherapy.cOm content 5 l 2l 2008 Schrader et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.Org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The tablet formulation of ritonavir-boosted lopinavir LPV r Kaletra has many advantages over the soft gel capsule SGC formulation including lower pill count no refrigeration requirement and no dietary restrictions. These advantages may help improve patient compliance and therefore increase adherence to treatment. However there are limited data regarding patient preferences and only recently was the comparative efficacy and tolerability data of LPV r SGC versus tablet formulation presented at an international conference. To address this deficit we conducted a market research survey to assess potential tolerability benefits patient satisfaction changes in adherence and formulation preference in patients switching from SGCs to .