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Pharmaceutical Substances Syntheses, Patents, Applications - Part 175. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Protheobromine p 1741 Reference s a Stoll A. et al. Helv. Chim. Acta HCACAV 16 703 1933 . Stoll A. Kreis w. Helv. Chim. Acta HCACAV 34 1431 1951 . Stoll A. et al. Helv. Chim. Acta HCACAV 35 2495 1952 . DRP 646 930 Ciba appl. 1933 CH-prior. 1932 . US 3 361 630 Knoll 2.1.1968 appl. 30.10.1964 D-prior. 2.11.1963 . b Louw P.G.J Nature London NATUAS 163 30 1949 . Zoller p. Tamm Ch. Helv. Chim. Acta HCACAV 36 1744 1953 . Formulationfs drg. 0.25 mg 0.5 mg Trade Name s D Talusin Knoll J Apocerpin Kotani Pros Tab. Mita F Talusin Biosedra wfm Bunosquin Seiko Proscillar Toyo Jozo I Caradrin Boehringer Ing. Caradrin Kowa Prosiladin Sawai wfm Cardiolidin Nichiiko Prosiladin Zeria Neogratusminal Simes - Cardion Nippon Proszin Teisan comb. wfm Chemiphar Scillaridin Moroshita Stellarid Zambeletti wfm Cardón Kanto Silamarin A Wakamoto Talusin Knoll wfm Mitredin Nippon Shoji Stellarid Tobishi-Mochida Teostellarid Zambeletti - Procardin Mohan Talusin Dainippon comb. wfm Procillan Hokuriku USA Talusin Knoll wfm Urgilan Simes wfm Proherz Shinshin Tradenal Knoll wfm Protheobromine atc C03BD Use diuretic cardiotonic RN 50-39-5 MF C10H14N4O3 MW 238.25 EINECS 200-034-8 LD50 580 mg kg M s.c. CN 3 7-dihydro-l- 2-hydroxypropyl 3 7-dimethyl-1H-purine-2 6-dione propylene oxide theobromine NaOH Referenced DE 1 067 025 Degussa appl. 23.8.1955 . Formulation s drg. 50 mg 100 mg Trade Name s D Cordabromin-Digoxin I Homburg -comb. wfm Antelin OFF -comb. wfm Idromin Amaldi wfm Tebe Simes wfm 1742 P Prothipendyl Prothipendyl ATC N05AX07 Use psychosedative neuroleptic RN 303-69-5 MF C16H19N3S MW 285.42 LD5 415 mg kg M p.o. 25 mg kg R i.v. CN V V-dimethyl-l0 -pyrido 3 2- l 4 benzothiazine-10-propanamine monohydrochloride RN 1225-65-6 MF C16H19N3S HC1 MW 321.88 EINECS 214-958-4 LD5 110 mg kg R i.v. 610 mg kg R p.o. 1. NoNH2 1. sodium omide 2. 3-dimethylomino- propyl chloride 1 -ozophenothiozine Prothipendyl Reference s DE 1 001 684 Degussa appl. 1954 . US 2 974 139 Degussa 7.3.1961 D-prior. 2.10.1954 . .