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Pharmaceutical Substances Syntheses, Patents, Applications - Part 166. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Piperazine P 1651 Formulation s amp. 1 g 10 ml 2 g 20 ml vial 1 g 1.5 g 2 g 3 g 4 g as sodium salt Trade Name s D Pipril Lederle 1980 F Pipérilline Wyeth-Lederle Tazocilline Wyeth-Lederle GB Pipril Wyeth-Lederle 1982 Tazocin Wyeth -comb. I Avocin Wyeth-Lederle 1982 Eril Savio IBN Tazocil Wyeth-Lederle -comb. J Penicillin Sankyo 1980 USA Pipracil Lederle 1982 Zasyn Lederle Piperazine atc P02CB01 Use anthelmintic RN 110-85-0 MF C4H10N2 MW 86.14 EINECS 203-808-3 LD 0 1180 mg kg M i.v. 600 mg kg M p.o. 1340 mg kg R i.v. 1900 mg kg R p.o. CN piperazine hexahydrate RN 142-63-2 MF C4HI0N2 6H2O MW 194.23 LD50 11.2 g kg M p.o. dihydrochloride RN 142-64-3 MF C4H10N2 2HC1 MW 159.06 EINECS 205-551-2 LDS 4900 mg kg R p.o. phosphate RN 1951-97-9 MF C4H10N2 xH3O4P MW unspecified EINECS 217-775-8 LDso 20 g kg M p.o. tartrate 1 1 RN 133-36-8 MF C4Hl0N2 C4H6O6 MW 236.22 EINECS 205-104-1 citrate 3 2 RN 144-29-6 MF C6H8O7 3 2C4H10N2 MW 642.66 EINECS 205-622-8 LDS0 8500 mg kg M p.o. 11200 mg kg R p.o. citrate 3 2 hydrate RN 41372-10-5 MF C6H8O2 3 2C4H10N2 xH2O MW unspecified edetate calcium 1 1 RN 12002-30-1 MF C10H14CaN2Og C4H10N2 MW 416.44 edetate calcium 1 1 dihydrate RN 50322-15-1 MF C10H14CaN2Og C4H10N2 2H2O MW 452.47 adipate 1 1 RN 142-88-1 MF C6H10O4 C4HI0N2 MW 232.28 EINECS 205-569-0 LDS0 8 g kg M p.o. 7900 mg kg R p.o. H2N- NH3 150-220 C 100-250 bar OH ---------------------------- H -N. N H ethanolomine Piperazine Reference s Ullmanns Encykl. Tech. Chem. 4. Aufl. Vol. 7 385. Formulation s tabl. 10 mg 1652 P Piperidolate Trade Name s D Girheulit Pflüger -comb. F Carudol Boehringer Ing. Vermifuge Sorin Sorin-Maxim GB Pripsen Seton -comb. I Citropiperazina Rhône- Poulenc Pharma J Bexin Tanabe USA Antepar Burroughs Wellcome wfm Piperidolate atc AO3AA3O Use anticholinergic antispasmodic RN 82-98-4 MF C21H25NO2 MW 323.44 EINECS 201-449-7 LD5 75 mg kg M i.v. 100 mg kg R i.v. CN a-phenylbenzeneacetic acid l-ethyl-3-piperidinyl ester hydrochloride RN 129-77-1 MF C21H25NO2 HC1 MW 359.90
