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Pharmaceutical Substances Syntheses, Patents, Applications - Part 204. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers. | Tiar amide T 2031 calcium salt FR 2 268 522 Roussel-Uclaf appl. 12.11.1969 . Clémence F. et al. Eur. J. Med. Chem. EJMCA5 9 390 1974 . salt with dibasic amino acids ES 460 926 Lab. Cusí appl. 21.7.1977 . Formulation s s. r. cps. 300 mg suppos. 300 mg tabl. 200 mg 300 mg Trade Name s D Surgam Albert-Roussel GB Surgam Florizel 1982 Hoechst 1981 I Surgamyl Roussel- J F Surgam Roussel 1975 Maestretti wfm Tioprofen Scharper wfm Surgam Roussel Tiaramide ATC M0i N02 . Use anti-inflammatory analgesic antipyretic RN 32527-55-2 MF C 5H18C1N3O3S MW 355.85 EINECS 251-083-7 LD50 564 mg kg M p.o. 3600 mg kg R p.o. . CN 4- 5-chloro-2-oxo-3 2H -benzothiazolyl acetyl -l-piperazineethanol monohydrochloride RN 35941-71-0 MF C15H18C1N3O3S HC1 MW 392.31 EINECS 252-802-7 LDS 178 mg kg M i.v. 564 mg kg M p.o. 203 mg kg R i.v. 2300 mg kg R p.o. 157 mg kg dog i.v. 4 g kg dog p.o. 5-chloro-2 3H - benzothiazolone k2co3 I 4- 1- 2-hydroxy-ethyl piperazine ethyl chloro-acetote Reference s DE 1 770 571 Fujisawa prior. 5.6.1968 . US 3 661 921 Fujisawa 9.5.1972 J-prior. 5.6.1967 30.9.1967 . US 3 755 327 Fujisawa 28.8.1973 J-prior. 5.6.1967 . Formulation s tabl. 50 mg 100 mg as hydrochloride 2032 T Tibezonium iodide Trade Name s I Ventaval Crinos wfm J Solantai Fujisawa 1975 Tibezonium iodide Tiabenzazoniumjodid ATC A01AB15 Use chemotherapeutic antiseptic antibacterial RN 54663-47-7 MF C28H32IN3S2 MW 601.62 EINECS 259-284-1 LD50 9 g kg M p.o. 10 g kg R p.o. CN V V-diethyl- V-methyl-2- 4- 4- phenylthio phenyl -3Z -l 5-benzodiazepin-2-yl thio ethanaminiuin iodide 4-acetyldiphenyl sulfide carbon tert-amylate 4-phenylthiobenzayl - diamine disulfide dithioacetic acid 4- 4-phenylthiophenyl - 2-diethylamino- 1 3-dihydro-2H-1 5-benzo- ethyl chloride diazepine-2-thione I 1. NoH 2. H3C I acetone 2. methyl iodide Reference s US 3 933 793 Recordati 20.1.1976 I-prior. 19.10.1971 18.5.1972 . GB 1 412 008 Recordati valid from 11.10.1972 I-prior. 19.10.1971 18.5.1972 . GB 1 412 009 Recordati valid from 11.10.1972
