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Pharmaceutical Substances Syntheses, Patents, Applications - Part 13. Reference containing a collection of 2267 active pharmaceutical ingredients, including those launched recently. Listed alphabetically according to their INNs and established a link between INNs, structure, synthesis and production processes, patent and literature situation, medical use, and trade names. For pharmacists and researchers | Ancitabine A 121 Ancitabine ATC L01BC Cyclooxytidine Use antineoplastic RN 31698-14-3 MF C9HhN3O4 MW 225.20 LDm 800 mg kg M Í.V. 3400 mg kg M p.o. 820 mg kg R Í.V. 7 g kg R p.o. CN 2 - 2a 3ß 3aß 9aß -2 3 3a 9a-tetrahydro-3-hydroxy-6-imino-6 7-furo 2 3 4 5 oxazolo 3 2-a pyrimidine-2-methanol monohydrochloride RN 10212-25-6 MF C9HnN3O4 HC1 MW 261.67 EINECS 233-515-6 LDJ I 800 mg kg M Í.V. 7 g kg M p.o. 820 mg kg R Í.V. 7 g kg R p.o. 344 mg kg dog i.v. cytidine POC13 H2O CH3COOC2H5 ------------ ----------- Reference s Kanal T. et al. Chem. Pharm. Bull. CPBTAL 18 2569 1970 . alternative syntheses Walwick E.R. et al. Proc. Chem. Soc. London PCSLAW 1959 84. Doerr L.L. Fox J.J. J. Org. Chem. JOCEAH 31 1465 1967 . Ruyle W.V. Shenn T.Y. L Med. Chem. JMCMAR 10 331 1967 . Kugawa K.K. Ichino M. Tetrahedron Lett. TELEAY 1970 867. The Merck Index 11th Ed. 663 Rahway 1991 . Formulation s amp. 10 mg 500 mg as hydrochloride Trade Name s J Cyclo-C Kohjin as hydrochloride Ancrod ATC C04A Use anticoagulant fibrinolytic RN 9046-56-4 MF unspecified MW unspecified EINECS 232-933-6 CN proteinase agkistrodon serine Fibrinolytic effecting protease enzyme with glycoprotein structure relative mol mass ca. 30000. Isolation from the poison secretion venom of Agkistrodon rhodostoma malayan pit viper with chromatographic purification. Reference s US 3 657 416 Natl. Res. Dev. Corp. London 18.4.1982 GB-prior. 21.2.1964 . Formulation s amp. 70 iu. 122 A Androstanolone Trade Name s D Arwin Knoll wfm GB Arvin Armour wfm Androstanolone ATC G03BB02 Stanolone Use androgen RN 521-18-6 MF C19H30O2 MW 290.45 EINECS 208-307-3 CN 5ot 17 ß -17-hydroxy andres tan-3-one ndrostenolone 1. h2 Pd-C 2. CrO3 CH-jCOOH ---------------- 3 17-ondrostonediane 1 1. SeO2 CH3OH 2. NaBH4 KOH 1. selenium dioxide 2. sodium borohydride Reference s US 2 927 921 Schering 8.3.1960 prior. 19.5.1954 24.1.1952 . alternative syntheses Butenandt A. et al. Chem. Ber. CHBEAM 68 2097 1935 . Ruzicka L. et al. Helv. Chim. Acta HCACAV 20 1557
