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Common DNA sequence variation influences 3-dimensional conformation of the human genome

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The 3-dimensional (3D) conformation of chromatin inside the nucleus is integral to a variety of nuclear processes including transcriptional regulation, DNA replication, and DNA damage repair. Aberrations in 3D chromatin conformation have been implicated in developmental abnormalities and cancer. |

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Common DNA sequence variation influences 3-dimensional conformation of the human genome

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