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Báo cáo khoa học: "The role of body mass index and diabetes in the development of acute organ failure and subsequent mortality in an observational cohor"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: The role of body mass index and diabetes in the development of acute organ failure and subsequent mortality in an observational cohort. | Available online http ccforum.eom content 10 5 R137 Research The role of body mass index and diabetes in the development of acute organ failure and subsequent mortality in an observational cohort Katarina Slynkova1 David M Mannino1 Greg S Martin2 Richard S Morehead1 and Dennis E Doherty1 Division of Pulmonary and Critical Care Medicine University of Kentucky Medical Center and Veteran s Administration Medical Center 740 South Limestone K 528 Kentucky Clinic Lexington KY 40536 USA 2Division of Pulmonary Allergy and Critical Care Emory University School of Medicine 49 Jesse Hill Jr Dr SE Atlanta GA 30303 USA Corresponding author David M Mannino dmannino@uky.edu Received 20 Jun 2006 Revisions requested 31 Jul 2006 Revisions received 10 Aug 2006 Accepted 25 Sep 2006 Published 25 Sep 2006 Critical Care 2006 10 R137 doi 10.1186 cc5051 This article is online at http ccforum.com content 10 5 R137 2006 Slynkova et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Several studies have shown a correlation between body mass index BMI and both the development of critical illness and adverse outcomes in critically ill patients. The goal of our study was to examine this relationship prospectively with particular attention to the influence of concomitant diabetes mellitus DM . Methods We analyzed data from 15 408 participants in the Atherosclerosis Risk in Communities ARIC study for this analysis. BMI and the presence of DM were defined at baseline. We defined acute organ failure as those subjects who met a standard definition with diagnostic codes abstracted from hospitalization records. Outcomes assessed included the following risk of the development of acute organ failure within three years of the .