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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Role of cardiac troponin as a prognosticator in critically ill patients. | Available online http ccforum.eom content 9 6 E30 Letter Role of cardiac troponin as a prognosticator in critically ill patients Andrew J Turley1 and Jacqui A Gedney2 Cardiology Specialist Registrar Cardiology General Adult Intensive Care Unit The James Cook University Hospital Marton Road Middlesbrough UK 2Consultant Anaesthetist and Intensivist Cardiology General Adult Intensive Care Unit The James Cook University Hospital Marton Road Middlesbrough UK Corresponding author Andrew J Turley Andrew.turley@nth.nhs.uk Published online 11 November 2005 This article is online at http ccforum.com content 9 6 E30 2005 BioMed Central Ltd Critical Care 2005 9 E30 DOI 10.1186 cc3920 See related research by King et al. in issue 9.4 http ccforum.com content 9 4 R390 In a recent issue of Critical Care Dr King and colleagues 1 described the role of cardiac troponin as a prognosticator in critically ill medical patients. They concluded that elevated troponin levels measured on admission are associated with an increased mortality rate. Our experience 2 supports that reported by King and coworkers. Our retrospective case note study conducted in 180 consecutive admissions to our general noncardio-thoracic intensive care unit over a 5-month period identified 62 patients with a raised troponin T TnT level. The all-cause mortality rate was 51.6 in those patients with a raised TnT as compared with 20.3 in patients with no TnT elevation P 0.001 . The median duration of admission was 5.5 days for patients with a raised TnT and 3 days for patients with a normal TnT P 0.003 . In over 70 of cases the raised TnT occurred within the first 72 hours of admission. Other groups have also reported that elevated biochemical markers of cardiac myocyte damage are common in critically ill patients and are associated with increased mortality 3 . TnT and troponin I are sensitive and specific for myocardial injury even at the microscopic level. Although the cardiac troponins are cardiospecific in many .
