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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Tidal breathing flow-volume loops in bronchiolitis in infancy: the effect of albuterol [ISRCTN47364493]. | Critical Care April 2001 Vol 6 No 2 Totapally et al. Research Tidal breathing flow-volume loops in bronchiolitis in infancy the effect of albuterol ISRCTN47364493 Balagangadhar R Totapally Cem Demerci George Zureikat and Brian Nolan Program Coordinator Pediatric Critical Care Fellowship Division of Critical Care Medicine Miami Children s Hospital Florida USA Director of Ambulatory Pediatrics Hurley Medical Center Flint Michigan USA Director of PICU Hurley Medical Center Flint Michigan USA Director of Pediatric Critical Care Hurley Medical Center Flint Michigan USA Correspondence Balagangadhar R Totapally bala.totapally@mch.com Received 14 August 2001 Revisions requested 17 October 2001 Revisions received 10 December 2001 Accepted 4 January 2002 Published 7 February 2002 Critical Care 2002 6 160-165 2002 Totapally et al. licensee BioMed Central Ltd Print ISSN 1364-8535 Online ISSN 1466-609X Abstract Objectives To evaluate the effect of nebulized albuterol on tidal breathing flow-volume loops in infants with bronchiolitis due to respiratory syncytial virus. Design A randomized double-blind control study. Setting Pediatric unit in a community teaching hospital. Participants Twenty infants younger than 1 year of age mean age 5.8 2.8 months with a first episode of wheezing due to respiratory syncytial virus bronchiolitis. Interventions Chloral hydrate 50 mg kg was administered orally for sedation. One dose each of nebulized albuterol 0.15mg kg in 3 ml saline and saline 3 ml were given at 6 hour intervals in a random order. Measurements Tidal breathing flow-volume loops were obtained before and after each aerosol treatment with a Neonatal Pediatric Pulmonary Testing System Model 2600 Sensor Medics Anaheim CA USA . At the same time the fraction of tidal volume exhaled at peak tidal expiratory flow PTEF to total tidal volume VPTEF VE and the fraction of exhaled time at PTEF to total expiratory time tPTEF tE were measured. The PTEF the tidal expiratory flows at 10 25 and 50
