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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione. | Respiratory Research BioMed Central Open Access Activation of chloride transport in CF airway epithelial cell lines and primary CF nasal epithelial cells by S-nitrosoglutathione Zhanna Servetnyk 1 Jelena Krjukova1 Benjamin Gaston2 Khalequz Zaman2 Lena Hjelte3 Godfried M Roomans1 and Anca Dragomir1 Address Department of Medical Cell Biology Uppsala University Uppsala Sweden 2Department of Pediatrics University of Virginia Health System Charlottesville VA USA and 3Stockholm CF Center Karolinska University Hospital Huddinge Stockholm Sweden Email Zhanna Servetnyk - Janna.Servetnyk@medcellbiol.uu.se Jelena Krjukova - Elena.Krjukova@medcellbiol.uu.se Benjamin Gaston - BMG3G@hscmail.mcc.virginia.edu Khalequz Zaman - KZ2N@hscmail.mcc.virginia.edu Lena Hjelte - lena.hjalte@karolinska.se Godfried M Roomans - Godfried.Roomans@medcellbiol.uu.se Anca Dragomir - Anca.Dragomir@medcellbiol.uu.se Corresponding author Published 05 October 2006 Received 13 February 2006 Respiratory Research 2006 7 124 doi 10.1186 1465-9921-7-124 Accepted 05 October 2006 This article is available from http respiratory-research.cOm content 7 l l24 2006 Servetnyk et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Background It has been suggested that low pM concentrations of S-nitrosoglutathione GSNO an endogenous bronchodilator may promote maturation of the defective cystic fibrosis CF transmembrane conductance regulator CFTR . Because nitric oxide NO and GSNO levels appear to be low in the CF airway there is an interest in the possibility that GSNO replacement could be of therapeutic benefit in CF. Methods The effect of GSNO on chloride Cl- transport was .
