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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học 'Respiratory Research cung cấp cho các bạn kiến thức về ngành y đề tài: " Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease. | Respiratory Research BioMed Central Research Open Access Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease Juan P de Torres 1 Ciro Casanova1 Angela Montejo de Garcini1 Armando Aguirre-Jaime1 and Bartolome R Celli2 Address Respiratory Research Unit Hospital Nuestra Sra de Candelaria Tenerife Spain and 2Pulmonary and Critical Care Division. Caritas-St. Elizabeth s Medical Center Boston USA Email Juan P de Torres - jupa65@hotmail.com Ciro Casanova - ccasanova@canarias.org Angela Montejo de Garcini - amontejo@hotmail.com Armando Aguirre-Jaime - aaguirre@canarias.org Bartolome R Celli - bcelli@copdnet.org Corresponding author Published 6 March 2007 Received 14 December 2006 Respiratory Research 2007 8 18 doi l0.ll86 l465-992l-8-l8 Accepted 6 March 2007 This article is available from http respiratory-research.cOm content 8 l l8 2007 de Torres et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Rationale We had shown that COPD women expressed more dyspnea than men for the same degree of airway obstruction. Objectives Evaluate gender differences in respiratory factors associated with dyspnea in COPD patients. Methods In a FEVl matched population of 100 men and women with COPD we measured age MMRC FEV1 FVC TLC IC TlC PaO2 PaCO2 DLCO Pimax P0.1 Ti Ttot BMI ffmi 6MWD and VAS scale before and after the test the Charlson score and the SGRQ. We estimated the association between these parameters and MMRC scores. Multivariate analysis determined the independent strength of those associations. Results MMRC correlated with BMI men -0.29 p 0.04 women -0.28 p 0.05 ffmi men -0.39 p 0.01 FEV1 men -0.64 p 0.001 women -0.29 p 0.04 FVC men -0.45 p 0.001 women -0.33 p 0.02 IC TLC men -0.52 p .
