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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis: a case report. | Lopez-Fernandez et al. Journal of Medical Case Reports 2011 5 98 http www.jmedicalcasereports.eom content 5 1 98 JOURNAL OF MEDICAL CASE REPORTS CASE REPORT Open Access Growth factor-enriched autologous plasma improves wound healing after surgical debridement in odontogenic necrotizing fasciitis a case report Rubi Lopez-Fernandez1 Jorge Ramirez-Melgoza1 Nora Ernestina Martinez-Aguilar2 Alicia Leon-Chavez2 Daniel Martinez-Fong3 Juan Antonio Gonzalez-Barrios2 Abstract Background Odontogenic necrotizing fasciitis of the neck is a fulminant infection of odontogenic origin that quickly spreads along the fascial planes and results in necrosis of the affected tissues. It is usually polymicrobial occurs frequently in immunocompromised patients and has a high mortality rate. Case presentation A 69-year old Mexican male had a pain in the maxillar right-canine region and a swelling of the submental and submandibular regions. Our examination revealed local pain tachycardia hyperthermia 39 C and the swelling of bilateral submental and submandibular regions which also were erythematous hyperthermic crepitant and with a positive Godet sign. Mobility and third-degree caries were seen in the right mandibular canine. Bacteriological cultures isolated streptococcus pyogenes and staphylococcus aureus. The histopathological diagnosis was odontogenic necrotizing fasciitis of the submental and submandibular regions. The initial treatment was surgical debridement and the administration of antibiotics. After cultures were negative the surgical wound was treated with a growth factor-enriched autologous plasma eight times every third day until complete healing occurred. Conclusions The treatment with a growth factor-enriched autologous plasma caused a rapid healing of an extensive surgical wound in a patient with odontogenic necrotizing fasciitis. The benefits were rapid tissue regeneration an aesthetic and a functional scar and the avoidance of further surgery and possible complications. .
