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Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học General Psychiatry cung cấp cho các bạn kiến thức về ngành y đề tài: Current approaches in the treatment of arthritic pain. | Available online http arthritis-research.eom content 9 3 214 Review Arthritis and pain Current approaches in the treatment of arthritic pain Bruce L Kidd Richard M Langford and Theresa Wodehouse William Harvey Research Institute Barts and The London Queen Mary School of Medicine and Dentistry Charterhouse Square London EC1M 6BQ UK Corresponding author BL Kidd b.l.kidd@qmul.ac.uk Published 11 June 2007 Arthritis Research Therapy 2007 9 214 doi 10.1186 ar2147 This article is online at http arthritis-research.com content 9 3 214 2007 BioMed Central Ltd Abstract Current evidence suggests that although persistent arthritic pain is initiated and maintained by articular pathology it is also heavily influenced by a range of other factors. Strategies for treating arthritic pain are therefore different from those adopted for acute pain. Although published guidelines offer general assistance the complexity of underlying mechanisms requires that measures designed to relieve pain must take into account individual biological psychological and societal factors. It follows that a combination of both pharmacological and non-pharmacological approaches offers the best opportunity for therapeutic success although determining the effectiveness of such complex interventions remains difficult. Pharmacological therapy is often prolonged and safety and tolerability issues become as important as efficacy over time. Introduction Arthritic pain is common and is associated with worse functional outcomes and poorer quality of life when compared with a range of other chronic conditions 1 . A bewildering array of guidelines and other evidence-based resources are available but the variability of therapeutic responses can lead to frustration and disappointment for both patients and health professionals. This review categorizes different pain states associated with arthritis and discusses the extent to which an understanding of underlying mechanisms can be used to inform the choice of analgesic .