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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Primary Kaposi sarcoma of the subcutaneous tissue | BioMed Central World Journal of Surgical Oncology Case report Primary Kaposi sarcoma of the subcutaneous tissue Liron Pantanowitz 1 John Mullen2 and Bruce J Dezube3 Open Access Address Department of Pathology Baystate Medical Center Tufts University School of Medicine Springfield MA USA 2Department of Surgery Beth Israel Deaconess Medical Center Harvard Medical School Boston MA USA and 3Department of Medicine Hematology-Oncology Beth Israel Deaconess Medical Center Harvard Medical School Boston MA USA Email Liron Pantanowitz - liron.pantanowitz@bhs.org John Mullen - jmullen@bidmc.harvard.edu Bruce J Dezube - bdezube@bidmc.harvard.edu Corresponding author Published 2 September 2008 Received 9 July 2008 World Journal of Surgical Oncology 2008 6 94 doi 10.1186 1477-7819-6-94 Accepted 2 September 2008 This article is available from http www.wjso.cOm content 6 1 94 2008 Pantanowitz et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Involvement of the subcutis by Kaposi sarcoma KS occurs primarily when cutaneous KS lesions evolve into deep penetrating nodular tumors. Primary KS of the subcutaneous tissue is an exceptional manifestation of this low-grade vascular neoplasm. Case presentation We present a unique case of acquired immune deficiency syndrome AIDS -associated KS manifesting primarily in the subcutaneous tissue of the anterior thigh in a 43-year-old male which occurred without overlying visible skin changes or concomitant KS disease elsewhere. Radiological imaging and tissue biopsy confirmed the diagnosis of KS. Conclusion This is the first documented case of primary subcutaneous KS occurring in the setting of AIDS. .