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Tuyển tập các báo cáo nghiên cứu khoa học ngành y học tạp chí Medical Sciences dành cho các bạn sinh viên ngành y tham khảo đề tài: Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis after coronary revascularization. | Int. J. Med. Sci. 2008 5 50 Research Paper International Journal of Medical Sciences ISSN 1449-1907 www.medsci.org 2008 5 2 50-61 Ivyspring International Publisher. All rights reserved Computerized two-lead resting ECG analysis for the detection of coronary artery stenosis after coronary revascularization Eberhard Grube1 Andreas Bootsveld2 Lutz Buellesfeld1 Seyrani Yuecel1 Joseph T Shen3 Michael Imhoff4 1. Department of Cardiology and Angiology HELIOS Heart Center Siegburg Siegburg Germany 2. Department of Cardiology Evangelisches Stift St. Martin Koblenz Germany 3. Premier Heart LLC Port Washington NY USA 4. Department for Medical Informatics Biometrics and Epidemiology Ruhr-University Bochum Bochum Germany Correspondence to Michael Imhoff MD PhD Am Pastorenwaldchen 2 D-44229 Dortmund Germany. Phone 49-231-973022-0 Fax 49-231-973022-31 e-mail mike@imhoff.de Received 2007.12.10 Accepted 2008.03.02 Published 2008.03.02 Background Resting electrocardiogram ECG shows limited sensitivity and specificity for the detection of coronary artery disease CAD where patients with a history of coronary revascularization may pose special challenges. Several methods exist to enhance sensitivity and specificity of resting ECG for diagnosis of CAD but such methods are not better than a specialist s judgement. We compared a new computer-enhanced resting ECG analysis device 3DMP to coronary angiography to evaluate the device s accuracy in detecting hemodynamically relevant CAD. Methods A convenience sample of 172 patients with a history of coronary revascularization scheduled for coronary angiography was evaluated with 3DMP before coronary angiography. 3DMP s sensitivity and specificity in detecting hemodynamically relevant coronary stenosis as diagnosed with coronary angiography were calculated as well as odds 1 ratios for the 3DMP severity score and coronary artery disease risk factors. Results The 3DMP system accurately identified 50 of 55 patients as having hemodynamically .
