Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Có một xu hướng chung cho việc thực hiện gần của những bệnh nhân này để cải thiện với thời gian trong suốt năm đầu tiên của nghiên cứu lâm sàng. Những lý do cho hiện tượng này chưa được biết. Có thể là cơ lông mi từ từ bắt đầu hoạt động trở lại sau khi năm bị bỏ đi. | 90 S.J.Dell There was a general tendency for the near performance of these patients to improve with time throughout the first year of clinical study. The reasons for this phenomenon are unknown. It is possible that the ciliary muscle slowly begins to function again after years of disuse. Another possible explanation is that a stiffer posterior capsule more effectively transfers force from the vitreous allowing more movement of the optic. Bilateral Implanted Subjects Wearing Spectacles n n I do not wear spectacles 33 128 25.8 1 Almost none of the time 61 128 47.7 j . 26 to 50 of the time 20 128 15.6 51 to 75 of the time 8 128 6.3 76 to 100 of the time 6 128 4.7 Night Spectacles n n No 110 128 84.6 Yes 20 130 15.4 Fig. 10.4. Spectacle use survey of FDA trial participants showed that 74 either did not wear spectacles or wore them almost none of the time The unusually small 4.5-mm optic initially sparked concerns among the clinical investigators that the Crystalens would create dys-photopsia in patients. The results of the trial demonstrated that this is not the case and Crystalens patients generally report night vision comparable to standard IOLs. In a substudy examining pupil size under 0.04 Lux scotopic conditions a questionnaire demonstrated minimal glare complaints despite average scotopic pupil sizes of 5.02 mm 8 . Studies of contrast sensitivity comparing the Crystalens to a traditional 6-mm Acrysof IOL have demonstrated comparable contrast sensitivity scores throughout the spatial frequency range 8 . Wavefront analysis has been used to demonstrate a refractive power change in Crystalens patients as they shift their gaze from near to distance fixation 9 . This is probably the most direct evidence of the accommodative abilities of these patients although such measurements are a challenge to obtain given current wavefront aberrometry technology. Variations in pupil size convergence during accommodation and lack of an accommodative target are just a few of the UBM
