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Tuyển tập các báo cáo nghiên cứu khoa học quốc tế về bệnh thú y đề tài: Random amplified polymorphic DNA (RAPD) analysis of Mycobacterium tuberculosis strains in India | J. Vet. Set. 2006 7 2 189-192 JOURNAL OF Veterinary Science Matricaria chamomilla CH12 decreases handling stress in Nelore calves Luis Souza Lima de Souza Reis Paulo Eduardo Pardo1 Eunice Oba2 Sergio do Nascimento Kronka3 Neuza Maria Frazatti-Gallma4 lDepartamento de Pos-graduapdo Universidade do Oeste Paulista UNOESTE Presidente Prudente SP CEP 19067-175 Brazil 2Departamento de Reproduqão Animal e Radiologia Faculdade de Medicina Veterinaria e Zootecnia Universidade Estadual Paulista Jitlio de Mesquita Filho UNESP Botucatu SP CEP 19067-175 Brazil 3Departamento de Pós-graduapão em Agronomia Universidade do Oeste Paulista UNOESTE Presidente Prudente SP CEP 19067-175 Brazil Seẹào de Raiva Instituto Butantan Sdo Paulo SP CEP 05503-900 Brazil Matricaria chamomilla CH12 is a phytotherapeutic or homeopathic product which has been used to reduce stress. Here we examined its effect on preventing handling stress in bovines. Sixty Nelore calves were randomly distributed into two equal groups. One group was administered Matricaria chamomilla CI112 in diet and the other the control was not. Animals in both groups were maintained unstressed for 30 days to adjust to the feeding system and pasture and were then stressed by constraint on the 31th 38th 45th and 60th experimental days. Blood samples were taken on these days after animals had been immobilization in a trunk contention for 5 min. Stress was followed by analyzing serum cortisol levels. These peaked on the 45th day and then decreased but not to baseline on the 60th day. On the 45th day cortisol levels were significantly lower in animals fed Matricaria chamomilla CH12 suggesting that this product reduces stress. These effects may be a consequence of its inhibiting cortisol production and its calming and anxiolytic effects. Key words bovine cortisol handling Matricaria charno-milla Nelore calf stress Introduction Neuroendocrine stress responses are regulated by the hypothalamic-pituitary-adrenal axis HPA which promotes .
