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Agricultural biotechnology offers great promise for Africa and tissue culture and marker-assisted selection are already in widespread use across the continent. However, the safe application of these technologies requires functioning biosafety systems. The report focuses on the special issues related to biosafety in Africa.Crops can be improved by conventional breeding, by tissue culture and by marker-aided selection. But for many improvements - such as drought and salinity tolerance - GM technology is going to be essential. Africans must be free to choose whether to develop and grow GM crops, without such strong-arm tactics from either side | Muffy Koch Patricia L. Traynor Robert Frederick The Agricultural Biotechnology Support Project Institute of International Agriculture Michigan State University USA A WO RKBOOK FOR TECHNICAL TRAINING Copyright 2002 by the Board of Trustees Michigan State University East Lansing MI All rights reserved. Printed in the United States of America. ISBN 1-56525-016-8 This publication was made possible through support provided by the U.S. Agency for International Development Bureau for Economic Growth Agriculture and Trade Office of Environment and Science Policy under the terms of Cooperative Agreement No. DAN-A-00-91-00126-00 and support of the U.S. Agency for International Development Cairo Egypt under the terms of Grant No. 263-G-00-96-00014-00. The opinions expressed herein are those of the author s and do not necessarily reflect the views of the U.S. Agency for International Development Michigan State University Virginia Polytechnic Institute and State University or the U.S. Environmental Protection Agency. PHOTO CREDITS pages vi 18 30 and 106 Scott Bauer courtesy of the Agricultural Research Service U.S. Department of Agriculture page 46 Francisco Santos Gonzales page 66 Kelly Zarka page 124 Jack Dykinga. ADDITIONAL COPIES OF THIS WORKBOOK ARE AVAILABLE FROM MSU Bulletin Office 10-B Agriculture Hall Michigan State University East Lansing MI 48824-1039 USA tel 517 355-0240 fax 517 353-7168. MANAGING EDITOR Andrea Johanson Assistant Director Agricultural Biology Support Project Michigan State University EDITOR Kathleen McKevitt IDIOM LAYOUT AND DESIGN Sharp Designs Inc. Lansing MI PRINTING AND BINDING BRD Printing Inc. Lansing MI CONTENTS Acknowledgments .v About the Authors .vii PART ONE Biosafety in Principle and in Introduction.3 Rationale and Objectives .3 Audience.4 Organization .5 Context for Biosafety Review and Decision Making.7 Factors Affecting Decision Making.7 Terms of Reference for Biosafety Committees.11 Resource Requirements.16 Risk Assessment.23 .