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A recent article in this journal, “The child health/family income gradient: Evidence from England” (Alison Currie, Michael A. Shields and Stephen Wheatley Price, 2007) argues that income gradients in the health of English children differ from those observed in either the US or Canada. Using data from the 1997 to 2002 Health Survey for England (HSE), Currie, Shields and Wheatley Price (CSW) conclude that English health gradients in income are small and increase little as children grow older. These findings are consistent with other research from England, which indicates that SES gradients in health that are present in earlier. | CJASN ePress. Published on July 22 2011 as doi 10.2215 CJN.10751210 Mini Review Insights from the Chronic Kidney Disease in Children CKiD Study Lawrence Copelovitch Bradley A. Warady and Susan L. Furth Summary Over the last 5 years the Chronic Kidney Disease in Children CKiD prospective cohort study has enrolled close to 600 children ages 1 to 16 years with mild to moderate chronic kidney disease CKD . The main purpose of this interim report is to review the initial cross-sectional data and conclusions derived from the clinical studies conducted within CKiD in the context of findings from other pediatric CKD and end-stage renal disease ESRD registry and cohort studies. In particular special emphasis was placed on studying four aspects of chronic kidney disease in children including the identification of risk factors related to disease progression the impact of CKD on neurocognition and quality of life QoL the cardiovascular morbidity associated with CKD and identifying the causes and effects of growth failure in the context of mild to moderate kidney failure. Clin J Am Soc Nephrol 6 2047-2053 2011. doi 10.2215 CJN.10751210 Introduction Over the last several decades several studies have reported on the demographic and clinical characteristics of children with CKD. Beginning in the 1990s two large prospective registries The North American Pediatric Renal Trials and Collaborative Studies NAPRTCS database and the ItalKid Project provided many important descriptions of the characteristics and comorbidities of children with CKD. These registries provided significant insight into underlying causes of CKD in children and rates of kidney function decline. Registry data are however limited by variations in measurement frequently missing longitudinal data and the absence of direct measures of kidney function. In 2005 in response to a request for applications from the National Institutes of Health NIH the Chronic Kidney Disease in Children CKiD prospective cohort study was .
