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Báo cáo khoa học: "An HPV 16 L1-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An HPV 16 L1-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice | Virology Journal BioMed Central Open Access An HPV 16 Ll-based chimeric human papilloma virus-like particles containing a string of epitopes produced in plants is able to elicit humoral and cytotoxic T-cell activity in mice Georgina Paz De la Rosa1 Alberto Monroy-Garcia2 3 María de Lourdes Mora-García2 Cristina Gehibie Reynaga Pena1 Jorge Hernandez-Montes2 Benny Weiss-Steider2 and Miguel Angel Gomez Lim 1 Address 1Centro de Investigación y de Estudios Avanzados CINVESTAV Unidad Irapuato Km. 9.6 Libramiento Norte 36500 Carretera Irapuato-León. Irapuato Guanajuato Mexico 2Laboratorio de Inmunobiología Unidad de Investigación en Diferenciacion Celular y Cancer. FES-Zaragoza UNAM México and 3Unidad de Investigación Médica en Enfermedades Oncológicas. IMSS CMN SXXI México Email Georgina Paz De la Rosa - ginapazz@yahoo.com Alberto Monroy-Garcia - albertomon@yahoo.com Maria de Lourdes Mora- Garcia - mogl@servidor.unam.mx Cristina Gehibie Reynaga Pena - creynaga@ira.cinvestav.mx Jorge Hernandez-Montes - jhzms@yahoo.com Benny Weiss-Steider - bennyweiss@hotmail.com Miguel Angel Gómez Lim - mgomez@ira.cinvestav.mx Corresponding author Published 6 January 2009 Received 26 November 2008 Accepted 6 January 2009 Virology Journal 2009 6 2 doi 10.1186 1743-422X-6-2 This article is available from http www.virologyj.cOm content 6 1 2 2009 De la Rosa et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Even though two prophylactic vaccines against HPV are currently licensed infections by the virus continue to be a major health problem mainly in developing countries. The cost of the vaccines limits wide-scale application in poor countries. A promising strategy for producing affordable and efficient vaccines involves the .