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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: An instrument to assess quality of life in relation to nutrition: item generation, item reduction and initial validation | Schunemann et al. Health and Quality of Life Outcomes 2010 8 26 http www.hqlo.eom content 8 1 26 HEALTH AND QUALITY of life outcomes RESEARCH Open Access An instrument to assess quality of life in relation to nutrition item generation item reduction and initial validation Holger J Schunemann1 Francesca Sperati2 Maddalena Barba2 Nancy Santesso3 Camilla Melegari4 Elie A Akl1 Gordon Guyatt3 Paola Muti2 Abstract Background It is arguable that modification of diet given its potential for positive health outcomes should be widely advocated and adopted. However food intake as a basic human need and its modification may be accompanied by sensations of both pleasure and despondency and may consequently affect to quality of life QoL . Thus the feasibility and success of dietary changes will depend at least partly on whether potential negative influences on QoL can be avoided. This is of particular importance in the context of dietary intervention studies and in the development of new food products to improve health and well being. Instruments to measure the impact of nutrition on quality of life in the general population however are few and far between. Therefore the aim of this project was to develop an instrument for measuring QoL related to nutrition in the general population. Methods and results We recruited participants from the general population and followed standard methodology for quality of life instrument development identification of population item selection n 24 item reduction n 81 item presentation n 12 pretesting of questionnaire and initial validation n 2576 construct validation n 128 and test-retest reliability n 20 . Of 187 initial items 29 were selected for final presentation. Factor analysis revealed an instrument with 5 domains. The instrument demonstrated good cross-sectional divergent and convergent construct validity when correlated with scores of the 8 domains of the SF-36 ranging from -0.078 to 0.562 19 out of 40 tested correlations were .
