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Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The first description of severe anemia associated with acute kidney injury and adult minimal change disease: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report The first description of severe anemia associated with acute kidney injury and adult minimal change disease a case report Yimei Qian Sushil K Mehandru Nancy Gornish and Elliot Frank Address Department of Medicine Jersey Shore University Medical Center 1945 Route 33 Neptune New Jersey 07754 USA Email Yimei Qian - yqian2005@hotmail.com Sushil K Mehandru - doc1732@aol.com Nancy Gornish - NGornish@meridianhealth.com Elliot Frank - EFrank@meridianhealth.com Corresponding author Published 23 January 2009 Received 16 May 2008 Journal of Medical Case Reports 2009 3 20 doi 10.1186 1752-1947-3-20 Accepted 23 January 2009 This article is available from http www.jmedicalcasereports.cOm content 3 l 20 2009 Qian et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http creativecommons.org licenses by 2.0 which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Acute kidney injury in the setting of adult minimal change disease is associated with proteinuria hypertension and hyperlipidemia but anemia is usually absent. Renal biopsies exhibit foot process effacement as well as tubular interstitial inflammation acute tubular necrosis or intratubular obstruction. We recently managed a patient with unique clinical and pathological features of minimal change disease who presented with severe anemia and acute kidney injury an association not previously reported in the literature. Case presentation A 60-year-old Indian-American woman with a history of hypertension and diabetes mellitus for 10 years presented with progressive oliguria over 2 days. Laboratory data revealed severe hyperkalemia azotemia heavy proteinuria and progressively worsening anemia. Urine eosinophils were not seen. Emergent hemodialysis erythropoietin and blood transfusion were .
