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Bệnh mô bào Langerhans (LCH) do Paul Langerhans phát hiện và mô tả năm 1868 là sự gia tăng của các tế bào đơn nhân đuôi gai khi xâm nhập vào các cơ quan khu trú hoặc khuếch tán. Hầu hết các trường hợp xảy ra ở trẻ em. Bài viết tập trung báo cáo ca bệnh mô tả bệnh lý xương thái dương do LCH ở trẻ em. | Vietnam Journal of Community Medicine Vol. 64 Special Issue 2023 164-172 INSTITUTE OF COMMUNITY HEALTH DESCRIPTION OF TEMPORAL BONE DISEASE CAUSED BY LCH IN CHILDREN CASE REPORT Nguyen Tuyet Xuong1 Pham Dang Hoang Giang1 Nguyen Xuan Nam1 Nguyen Khac Truong1 Trinh Duy Nin1 Tran Thai Son1 Vu Toan Manh1 Than Huu Tiep1 Nguyen Thi Ngoc Ha1 Do Hong Diep1 Vu Ngoc Quy1 Nguyen Thi Anh Hong1 Nguyen Phuong Dung1 Ngo Minh Thuan1 Nguyen Dac Cu1 Nguyen Minh Hang1 Dao Hoa Phuong1 Nguyen Hoang Huy2 Nguyen Thi To Uyen2 Vuong Dinh Anh Tu3 Pham Phuc Khanh3 Vietnam National Children s Hospital - 879 18 La Thanh street Lang Thuong Dong Da Hanoi Vietnam 1 2 National Otorhinorarynology Hospital of Vietnam - 78 Giai Phong Phuong Dinh Dong Da Ha Noi Vietnam 3 Hanoi Medical University - 1 Ton That Tung Kim Lien Dong Da Hanoi Vietnam Received 01 03 2023 Revised 06 04 2023 Accepted 10 05 2023 ABSTRACT Langerhans cell histiocytosis LCH was discovered and described by Paul Langerhans in 1868 as an increase in dendritic mononuclear cells when entering localized or diffuse organs. Most cases occur in children. Manifestations may include pulmonary infiltrates bone damage rash and dysfunctions of the liver blood-forming and endocrine organs. Diagnosis is based on biopsy. Poor prognostic factors include lt age 2 years and multi-organ symptoms involving the hematopoietic system liver spleen or combination. Treatments include chemotherapy or local treatment with surgery or radiation therapy based on the extent of the disease. LCH has an incidence of 1 in 50 000 to 1 in 200 000 children in children accounting for 5 to 8 children per 1 million children. We refered the 3 cases diagnosed with LCH with temporal bone lesions at the Department of Otolaryngology National Hospital of Pediatrics. Keywords Langerhans cell histiocytosis LCH children. Corressponding author Email address nguyenxuongnhp@yahoo.com Phone number 84 985285385 164 N.T. Xuong et al. Vietnam Journal of Community Medicine Vol. 64 Special .
