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This study investigates the possible synergistic stimulatory effects of prebiotic chitooligosaccharide and some commercial prebiotics on probiotic growth. Different combination of chitooligosaccharide with inulin, fructooligosaccharide, and lactulose were prepared and their ability to stimulate the growth of probiotic strains was evaluated. Following Chou-Talalay method, the combination index was calculated and used for synergistic assessment. |
