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Neonatal septicemia continues to be a major cause of mortality and morbidity among neonates around the world, in spite of great advances in antimicrobial therapy, neonatal life support measures and the early detection of risk factors. The present study was undertaken to describe the spectrum of isolates in cases of neonatal septicaemia, and their antimicrobial susceptibility pattern and to look for their association with various risk factors. In this prospective study in central India we prospectively enrolled the suspected cases of neonatal septicaemia, which were not on antimicrobials. One to two millilitre of blood from these neonates was cultured in brain heart infusion broth. Blood Culture and Antibiotic susceptibility testing were performed as per standard protocols. Detailed history and clinical findings were recorded. | Neonatal septicemia: Bacteriology and risk factors in a tertiary care hospital of central India