TAILIEUCHUNG - Evaluation of C-Reactive protein (CRP) in early diagnosis of Neonatal Septicemia

Neonatal septicemia constitutes a significant cause of neonatal mortality & morbidity in developing countries. It becomes essential to diagnose it as early as possible to reduce the mortality and treat with appropriate antibiotics. CRP is a sensitive & good inflammatory marker. Definite diagnosis of septicemia depends on positive blood culture, which takes around 48-72 hrs. Result of CRP test is available within an hour in tertiary care centers and remote areas, where there is no availability of well equipped laboratory setup for blood culture. 315 Neonates with suspected sepsis were included. Under aseptic precautions, Blood samples were collected in blood culture bottle & in Plain Vaccute. The CRP test was done by rapid slide latex agglutination method using the diagnostic kit (Tulip Diagnostics Ltd). Repeated Subcultures were performed. Identification of Organisms and Antibiotic sensitivity testing were done. Out of 315 cases, 180 (57%) had positive CRP and 135(43%) cases had positive blood culture. The Most common organism isolated were Gram negative organisms (65% ) like Klebsiella 56(41%) followed by Pseudomonas 19(14%), E. coli 11(8%), and Gram positive organisms (35%) like CONS 39(29%), Staphylococcus aureus 08(6%) . Estimation of CRP is easy to perform, rapid. It can use as inflammatory marker in early diagnosis of neonatal septicemia which will help to prevent severe and life threatening complications. | Evaluation of C-Reactive protein (CRP) in early diagnosis of Neonatal Septicemia

• Y khoa - Dược
• Neonatal septicemia
• Blood culture
• C Reactive protein
• Early diagnosis
• Neonatal Septicemia
• Antibiotic susceptibility
• Clinical isolates
• Clinical isolates of neonatal septicemia
• Antibiotic susceptibility pattern
• Metallo beta lactamase
• Gram negative bacteria
• HAHC hospital
• Cases of neonatal septicemia
• Metallo beta lactamase production
• Sepsis screen
• Predicting neonatal septicemia
• Sepsis screen tests
• Creactive protein
• Early diagnosis of neonatal septicemia
• Bacteriological spectrum
• Neonatal intensive care unit
• Staphylococcus aureus
• Gram negative bacilli
• Onset septicemia
• Microbiological profile
• Antibiotic sensitivity patterns
• Developing countries
• Neonatal sepsis
• Antibiogram of neonatal septicemia
• Tertiary care hospital
• Bacteriology laboratory
• Escherichia coli
• Klebsiella pneumoniae
• ESBL in isolates of Klebsiella Pneumoniae
• Antibiotic susceptibility patterns
• MGM hospital
• Methicillin resistant staphylococcus aureus
• Incidence of methicillin resistant
• Challenges in management
• BMC Pediatrics
• Bacterial profile
• Antimicrobial susceptibility
• Multidrug resistant
• Bacteriological profile
• Antibiotic sensitivity
• Western U P
• Mortality despite considerable progress
• Neonatal septicaemia
• Perinatal risk factors
• Antimicrobial resistance
• Gram negative septicaemia