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Gram negative enteric bacilli are a leading cause for sepsis in children and adults. The infections caused by Enterobacteriaceae are community and hospital-acquired. These bacteria have the potential to spread in the hospital environment and also across continents. Current study was designed to characterise Escherichia coli isolates from blood stream infection and identify the genes responsible for carbapenemase production and correlate the results with MHT. | Accurate and timely identification of genes conferring resistance to carbapenems serves as an important tool for infection control measures