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The experiment was conducted to determine the effects of four amino acids (lysine, methionine, threonine and tryptophan) supplementation on growth performances and serum antibody titers to Gumboro disease (IBD, infectious bursal disease) in broiler chickens. Chicks were randomly assigned to 5 dietary groups (5 chicks/group as 12 replicates of 5 chicks) in a complete randomised experimental design. | 29 Nong Lam University, Ho Chi Minh City Effects of lysine, methionine, threonine and tryptophan on growth performance and serum antibody titers to Gumboro disease of color feather chicken Duong Chi Mai, Duong Duy Dong and Dang Thi Nguyen Huong Nong Lam University, Ho Chi Minh City, Vietnam ARTICLE INFO ABSTRACT The experiment was conducted to determine the effects of four amino acids (lysine, methionine, threonine and tryptophan) supplementation on growth performances and serum antibody titers Recieved: May 07, 2018 to Gumboro disease (IBD, infectious bursal disease) in broiler Accepted: November 28, 2018 chickens. Chicks were randomly assigned to 5 dietary groups (5 chicks/group as 12 replicates of 5 chicks) in a complete randomised experimental design. Group I served as control group, was fed a diet without any supplementation. Groups II and III Keywords were supplemented 10% of four amino acids (lysine, methionine, threonine and tryptophan) of the recommended requirements Broiler chickens for 45 and 42 days, respectively. Meanwhile, Groups IV and V Lysine were supplemented 20% of four amino acids (lysine, methionine, Methionine threonine and tryptophan) of the recommended requirements for 45 and 42 days, respectively. The supplementation was started Threonine Tryptophan and antibody titres against at 3 days of age in chicks. The chickens were vaccinated against Gumboro disease at day 12 and day 19. The antibody titer of the Gumboro disease chickens in each group was assayed using IBD anti-body ELISA. Besides, the live body weight, average feed intake and feed conversion (FCR) were determined at 0, 21, 42 and 84 days of age. The results showed no significant different between groups in performance parameters such as body weight and FCR. HowCorresponding author ever, the present work showed highest dose of lysine, methionine, threonine and tryptophan supplementation for 42 days may Duong Chi Mai be improved feed intake and immune response of chicken .