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Monitoring of citrulline and diamine oxidase levels as biomarkers for intestinal mucositis during early-phase hematopoietic cell transplantation

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Gastrointestinal tract mucositis is a common side effect in the early phase of hematopoietic cell transplantation（HCT）, although reliable biomarkers have not yet been established. Since blood levels of citrulline and diamine oxidase（DAO）have been reported as specific markers of intestinal mucosal injury during cytotoxic cancer chemotherapy, we aimed to evaluate the relationship between circulating citrulline／DAO levels and the severity of gastrointestinal mucosal injury in patients with hematologic diseases who had undergone various types of HCT. | Monitoring of citrulline and diamine oxidase levels as biomarkers for intestinal mucositis during early-phase hematopoietic cell transplantation

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