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Objectives: To compare testosterone and gonadotropins characteristics of cryptorchidism in male adults before and after orchidopexy. Subjects and methods: In a follow-up study on 112 adult patients, who were operatived by orchidopexy. | Journal of military pharmaco-medicine no4-2018 TESTOSTERONE AND GONADOTROPINS IN MALE ADULTS WITH CRYPTORCHIDISM: COMPARE PRE- AND POST-ORCHIDOPEXY Nguyen Manh Thang*; Tran Quan Anh**; Nguyen Quang** SUMMARY Objectives: To compare testosterone and gonadotropins characteristics of cryptorchidism in male adults before and after orchidopexy. Subjects and methods: In a follow-up study on 112 adult patients, who were operatived by orchidopexy. Analyzing characteristics of their hormones including LH, FSH, testosterone, compared pre- and post-operation. Results: Mean age was 25.69 ± 5.7 (15 - 43 years old). Average LH/FSH/testosterone. Pre-orchidopexy: unilateral 6.7 ± 2.6/8.8 ± 6.9/17.0 ± 5.9. Bilateral: 11.6 ± 6.0/22.0 ± 13.7/14.5 ± 7.3. Post orchidopexy: average LH/FSH/testosterone were different between two groups: unilateral 5.8 ± 2.0/7.2 ± 5.3/18.8 ± 4.9. Bilateral 8.4 ± 3.6/15.6 ± 9.8/16.2 ± 5.8. Average LH, FSH decreased. Average testosterone increased. Conclusions: There is an improvement in testosterone and gonadotropin in male adults with cryptorchidism post-operation, althought there is difference between two groups: bilateral and unilateral. * Keywords: Adult cryptorchidism; Testosterone; Gonadotropins; Orchidopexy. INTRODUCTION Cryptorchidism is one of the most common congenital condition in the pediatric population. This is a disorder in which one or both of the testes do not descend spontaneously to the usual position in the scrotum. About 3% of fullterm and 30% of premature infant boys are born with at least one undescended testis [2, 6, 10]. Cryptorchidism is more commonly seen in premature males because the testes do not descend from the abdomen to the scrotal sac until the seventh month of fetal development [2, 8]. Cryptorchidism is associated with impairment of germ cell maturation and subsequent infertility in adulthood. It's common knowledge that the increased temperature in undescended testis affects spermatogeneis rather than hormonal levels .