PARP inhibitor trang 1 tải miễn phí từ TAILIEUCHUNG

"PARP inhibitor" trang 1 - tải miễn phí từ Tailieuchung

Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: A case report

Polyclonal BRCA2 mutations following carboplatin treatment confer resistance to the PARP inhibitor rucaparib in a patient with mCRPC: A case report

6 71 0

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib

Study protocols of three parallel phase 1 trials combining radical radiotherapy with the PARP inhibitor olaparib

13 40 0

Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells

Anti-tumor activity of olaparib, a poly (ADP-ribose) polymerase (PARP) inhibitor, in cultured endometrial carcinoma cells

10 26 1

Inhibition of PI3K-AKT-mTOR pathway sensitizes endometrial cancer cell lines to PARP inhibitors

Inhibition of PI3K-AKT-mTOR pathway sensitizes endometrial cancer cell lines to PARP inhibitors

11 15 1

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

Correlation of homologous recombination deficiency induced mutational signatures with sensitivity to PARP inhibitors and cytotoxic agents

13 39 3

A phase IA dose-escalation study of PHI101, a new checkpoint kinase 2 inhibitor, for platinum-resistant recurrent ovarian cancer

A phase IA dose-escalation study of PHI101, a new checkpoint kinase 2 inhibitor, for platinum-resistant recurrent ovarian cancer

7 26 3

Radiosensitization with combined use of olaparib and PI-103 in triple-negative breast cancer

Radiosensitization with combined use of olaparib and PI-103 in triple-negative breast cancer

9 21 1

PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models

PARP inhibition and the radiosensitizing effects of the PARP inhibitor ABT-888 in in vitro hepatocellular carcinoma models

10 27 1

A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells

A type I combi-targeting approach for the design of molecules with enhanced potency against BRCA1/2 mutant- and O6-methylguanine-DNA methyltransferase (mgmt)- expressing tumour cells

12 70 1

Sequential therapeutic targeting of ovarian Cancer harboring dysfunctional BRCA1

Sequential therapeutic targeting of ovarian Cancer harboring dysfunctional BRCA1

9 26 1

Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer

Lack of MRE11-RAD50-NBS1 (MRN) complex detection occurs frequently in low-grade epithelial ovarian cancer

9 59 1

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide

12 28 1

$Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy$

Phase II study of olaparib in patients with refractory Ewing sarcoma following failure of standard chemotherapy

6 35 1

Homologous recombination proficiency in ovarian and breast cancer patients

Homologous recombination proficiency in ovarian and breast cancer patients

12 22 1

Pharmacogenomic analysis of patientderived tumor cells in gynecologic cancers

Pharmacogenomic analysis of patientderived tumor cells in gynecologic cancers

13 51 3

Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer

Homologous recombination deficiency in diverse cancer types and its correlation with platinum chemotherapy efficiency in ovarian cancer

11 9 1

PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts

PARP inhibitors combined with ionizing radiation induce different effects in melanoma cells and healthy fibroblasts

10 19 1

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