Đang chuẩn bị nút TẢI XUỐNG, xin hãy chờ
Tải xuống
Research objectives: To analyse of obstetric history and characteristics of anticardiolipin antibody and lupus anticoagulant in pregnant women with a history of RPL; assess the effectiveness of treatment pregnancy in women with a history of RPL by antiphospholipid syndrome by coordinating regimen low doses of aspirin and low molecular weight heparin. | 1 INTRODUCTION 1. Urgency of topics Recurrent pregnancy loss RPL are a common maternity pathology affects 1-3 pregnancy. RPL is defined as having 3 times more consecutive miscarriages eliminating cases of ectopic pregnancy hydartiform mole and fetal biochemical abortion should under 20 weeks. The most common causes and can be cured completely of RPL is antiphospholipid syndrome APS the antiphospholipid antibody aPL causes thrombose in the placenta vessels which triggers RPL in the first 3 months stillbirth fetal growth retardation or premature severe preeclampsia and so on. Diagnosis and treatment APS can raise the live birth rate from 20 up to 80 . Since 2009 Vietnam obstetricians has begun to learn and initially identified the role of APS in RPL. However obstetric physicians realize that there are many obstacles in the application of criteria for diagnosing subclinical syndrome in patient populations of RPL. Several studies conducted in Vietnam has not yet fully examined the two main types of aPL or not tested twice for patients with positive result to eliminate fault positive cases. Therefore the theme Research antiphospholipid syndrome in pregnant women with a history of RPL by 12 weeks was conducted with two objectives 1 To analyse of obstetric history and characteristics of anticardiolipin antibody and lupus anticoagulant in pregnant women with a history ofRPL. 2 To assess the effectiveness of treatment pregnancy in women with a history of RPL by antiphospholipid syndrome by coordinating regimen low doses of aspirin and low molecular weight heparin. 2 2. New contributions of topics 1 Research conducted on a large enough sample 301 pregnant women with a history of RPL and patients have been tested 2 main antibodies aCL and LA. The study tested 2 times for the positive cases in order to eliminate all cases of transient positive. The study results showed that is the most common cause of RPL accounted for 11 29 . 2 The study has identified the primary aPL in RPL
