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Designations used by companies to distinguish their products are often claimed as trademarks. All brand names and product names used in this book are trade names, service marks, trademarks or registered trademarks of their respective owners. The publisher is not associated with any product or vendor mentioned in this book. This publication is designed to provide accurate and authoritative information in regard to the subject matter covered. It is sold on the understanding that the publisher is not engaged in rendering professional services. If professional advice or other expert assistance is required, the services of a competent professional should be. | A Practical Approach to Cardiovascular Medicine To my mother Masoumeh Toti for her continuous support and love. and To my mentor Irv Weissman for being a true role model and a source of inspiration. R.A. To my wife Mabel for bringing so much love and joy to my life. M.P. To my wonderful wife Gloria and to my beautiful daughters Catherine and Margaret. anA To the memory of my loving parents Lillian and Samuel. P.W. Reza Ardehali Marco Perez Paul Wang Openmirrors.com A Practical Approach to Cardiovascular Medicine EDITED BY Reza Ardehali MD PhD Department of Internal Medicine Division of Cardiology Stanford University School of Medicine Stanford CA USA Marco Perez MD Department of Internal Medicine Division of Cardiology Stanford University School of Medicine Stanford CA USA Paul Wang PhD Department of Internal Medicine Division of Cardiology Stanford University School of Medicine Stanford CA USA WILEY-BLACKWELL A John Wiley Sons Ltd. .