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(BQ) Part 2 book "The Bethesda system for reporting cervical cytology" presents the following contents: Epithelial cell abnormalities - squamous, epithelial abnormalities - glandular, other malignant neoplasms, anal cytology, adjunctive testing, computer assisted interpretation of cervical cytology, educational notes and comments appended to cytology reports, risk assessment approach to management,. | Epithelial Cell Abnormalities Squamous 5 Michael R. Henry Donna K. Russell Ronald D. Luff Marianne U. Prey Thomas C. Wright Jr and Ritu Nayar 5.1 Epithelial Cell Abnormalities Squamous Cell Squamous Intraepithelial Lesion SIL - Low-grade squamous intraepithelial lesion LSIL - High-grade squamous intraepithelial lesion HSIL With features suspicious for invasion if invasion is suspected Squamous cell carcinoma M.R. Henry MD Department of Laboratory Medicine Mayo Clinic 200 1st Street SW Rochester MN 55905 USA e-mail henry.michael@mayo.edu D.K. Russell CT ASCP HT MEd Department of Pathology and Laboratory Medicine University of Rochester Medical Center 601 Elmwood Avenue 626 Rochester Ny 14642 USA e-mail donna_russell@urmc.rochester.edu R.D. Luff MD MPH Anatomic Pathology Division for Clinical Trials Quest Diagnostics Teterboro NJ 07608 USA e-mail ronald.d.luff@questdiagnostics.com M.U. Prey MD 8829 Ladue Road Ladue Missouri 63124 USA e-mail marianne@extravirginoo.com T.C. Wright Jr MD Department of Pathology and Cell Biology Columbia University 631 W 168th St New York NY 10032 USA e-mail tcw1@cumc.columbia.edu R. Nayar MD Department of Pathology Feinberg School of Medicine Northwestern University Northwestern Memorial Hospital 251 East Huron Street Galter Pavilion 7-132B Chicago IL 60611 USA e-mail r-nayar@northwestern.edu Springer International Publishing Switzerland 2015 135 R. Nayar D.C. Wilbur eds. The Bethesda System for Reporting Cervical Cytology Definitions Criteria and Explanatory Notes DOI 10.1007 978-3-319-11074-5_5 136 M.R. Henry et al. 5.2 Background Squamous abnormalities encompass the spectrum of noninvasive cervical epithelial abnormalities associated with human papillomavirus HPV ranging from the cellular changes that are associated with transient HPV infection to those representing high-grade precursors to invasive squamous cell carcinoma. It has now been well established that HPV is the main causal factor in the pathogenesis of virtually all .
