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(BQ) Part 2 book "Netter's essential histology" presents the following contents: Integumentary system, upper digestive system, lower digestive system, respiratory system, urinary system, male reproductive system, female reproductive system, female reproductive system, special sense, liver, gallbladder and exocrine pancreas. | 11 INTEGUMENTARY SYSTEM 11.1 Overview 11.2 Histology of Thick and Thin Skin 11.3 Histology of the Epidermis 11.4 Ultrastructure of the Epidermis 11.5 Ultrastructure of Keratinocytes 11.6 Histology and Function of Epidermal Melanocytes 11.7 Ultrastructure of Melanocytes and Melanogenesis 11.8 Structure and Function of Epidermal Langerhans Cells 11.9 Histology and Vasculature of the Dermis 11.10 Histology and Innervation of the Dermis 11.11 Histology and Function of Eccrine Sweat Glands 11.12 Histology and Function of Apocrine Sweat Glands 11.13 Histology of Pilosebaceous Units Hair 11.14 Histology and Function of Pilosebaceous Units Hair Follicles and Hair Growth 11.15 Ultrastructure of Hair and its Follicles 11.16 Histology of Sebaceous Glands and Arrector Pili Muscles 11.17 Ultrastructure and Function of Sebaceous Glands 11.18 Anatomy and Histology of Nails 11.19 Histology of Psoriasis 243 244 Integumentary System Arrector muscle of hair Hair shaft Pore of sweat gland Sebaceous gland Hair follicle Sweat gland Hair matrix Papilla of hair follicle Pacinian corpuscle Subcutaneous artery vein and nerve Schematic of skin and its appendages that shows the epidermis dermis and subcutaneous tissue. 11.1 OVERVIEW The integument the largest organ of the body is composed of skin and skin appendages nails hair sweat glands and sebaceous glands. The total weight and overall surface area of skin in the adult are 3-5 kg and 1.5-2 m2 respectively. Skin thickness between 0.5 and 3 mm varies regionally skin is thickest on the back and thinnest on the eyelid. At mucocutaneous junctions skin is continuous with mucous membranes lining digestive respiratory and urogenital tracts. As well as serving as a protective barrier against injury e.g. abrasions cuts burns infectious pathogens and ultraviolet UV radiation skin assists in body temperature regulation vitamin D synthesis ion excretion and sensory reception touch and pain and it has a remarkable regenerative capacity. It consists of