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The 3 billion base pair sequence of the human genome is now available, and attention is focusing on annotating it to extract biological meaning. I will discuss what we have obtained, and the methods that are being used to analyse biological sequences. In particular I will discuss approaches using stochastic grammars analogous to those used in computational linguistics, both for gene finding and protein family classification. | Interpreting the human genome sequence using stochastic grammars Richard Durbin The Sanger Centre Wellcome Trust Genome Campus Hinxton Cambridge CB10 1SA UK rd@sanger.ac.uk Abstract The 3 billion base pair sequence of the human genome is now available and attention is focusing on annotating it to extract biological meaning. I will discuss what we have obtained and the methods that are being used to analyse biological sequences. In particular I will discuss approaches using stochastic grammars analogous to those used in computational linguistics both for gene finding and protein family .