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Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of | DOWN SYNDROME Edited by Subrata Kumar Dey Down Syndrome http dx.doi.org 10.5772 46009 Edited by Subrata Kumar Dey Contributors Kazuko Kudo Melanie Pritchard Érika Cristina Pavarino Joice Matos Biselli Eny Maria Goloni Bertollo Walter Pinto Júnior Francisco Javier Ordonez Volney Sheen Jie Lu A K M Mamunur Rashid George Grouios Antonia Ypsilanti Irene Koidou Darija Mateja Strah Maja Pohar-Perme Ksenija Gersak Ferdinando Di Cunto Gaia Berto Gislaine Czlusniak Ana Paula Teitelbaum Sujoy Ghosh Subrata Kumar Dey Jaana Marttala Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2013 InTech All chapters are Open Access distributed under the Creative Commons Attribution 3.0 license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Dejan Grgur Technical Editor InTech DTP team Cover InTech Design team First published February 2013 Printed in Croatia A free online edition of this book is available at www.intechopen.com Additional hard copies can be obtained from orders@intechopen.com Down Syndrome Edited by Subrata Kumar Dey p. cm. ISBN .